Bus Tickets from Karlsruhe to Brussels

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TodayMay 3
from $42
TomorrowMay 4
from $111
MonMay 5
from $82
TueMay 6
from $63
WedMay 7
ThuMay 8
from $47
FriMay 9
from $36
SatMay 10

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 4 at
    Departure city: Karlsruhe
    Departure location: Karlsruhe
    Arrival time: May 4 at
    Destination city: Brussels
    Destination location: Brussels-South (Gare du Midi)
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: May 4 at
    Departure city: Karlsruhe
    Departure location: Karlsruhe
    Arrival time: May 5 at
    Destination city: Brussels
    Destination location: Brussels-South (Gare du Midi)
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:

Accepted payments

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Compare 3 ways to go from Karlsruhe to Brussels.

Average Price$27 - $225Average Duration13h 5m
9kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average Price$44 - $227Average Duration4h 48m
9kg CO₂e5 out of 5 stars
Fastest
Carpool
Average Price$45 - $45Average Duration5h 30m
15kg CO₂e4 out of 5 stars
busbud logoBusbud recommends carpooling from Karlsruhe to Brussels

Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 5 hours 30 minutes and with fares starting at just $45, it presents an excellent value for a comfortable ride.

1carpool per day
5h 30mAverage Duration
$45Cheapest ticket
15kgCO₂ emissions

Bus Karlsruhe to Brussels: Trip Overview

Average ticket price$69
Average bus trip duration13h 5m
Number of daily buses2
Earliest bus departure12:25am
Distance221 miles (356 km)
Latest bus departure11:10pm

Karlsruhe to Brussels Bus

Busbud helps you find a bus from Karlsruhe to Brussels. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Karlsruhe to Brussels will be provided by the most trusted bus companies.

Discover how much the bus trip from Karlsruhe to Brussels will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Karlsruhe - Brussels

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/01
$38
05/02
$38
Today
$42
05/04
$110
05/05
$82
05/06
$63
05/07
$88
05/08
$47
busbud logoThe cheapest trip from Karlsruhe to Brussels was searched and found on May 2, 2025 with a price of $38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Brussels, as early as possible.

You can expect to pay from $38 to $140 for a bus ticket from Karlsruhe to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $47 which is on 2025-05-08.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Karlsruhe and Brussels!

Much more than a mere vehicle taking you from Karlsruhe to Brussels, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Karlsruhe to Brussels will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Karlsruhe to Brussels, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Karlsruhe by bus?

Bus from Karlsruhe to Brussels

You can also go to Brussels by train

Train from Karlsruhe to Brussels

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