Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Louisville, KY | Madisonville, USA | CheapestFastest |
Last refresh of the prices: Today at 1:08 AM EST.
Get from Louisville to Madisonville
The journey takes about 6 hours and with fares starting at just $76, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Louisville to Madisonville by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Louisville to Madisonville?
The cheapest bus tickets from Louisville to Madisonville start from $76. The average price for this route is around $115. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Louisville to Madisonville?
The average bus trip duration from Louisville to Madisonville is 6h, covering a distance of 115 miles (185 km). The quickest bus can get you there in 6h and is operated by Greyhound.
Which bus companies service the Louisville to Madisonville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Louisville to Madisonville?
The earliest bus departs from Louisville to Madisonville at 6:05am. And the latest bus departs at 6:05am.
What are the CO₂ emissions for the bus trip from Louisville to Madisonville?
A bus trip from Louisville to Madisonville generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Louisville to Madisonville was searched and found on Dec 11, 2025 with a price of $102To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Madisonville, as early as possible.
You can expect to pay from $102 to $107 for a bus ticket from Louisville to Madisonville based on the last 2 days. You can expect to find the cheapest price for the trip at $102 which is on 2025-12-11.
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