Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lyon Avenue Tony Garnier | Rome Tiburtina Bus Station | Cheapest | ||||
 | Bus | Gare routière de Gerland | Rome Tiburtina Bus Station | Fastest | ||||
 | Bus | Lyon - Gerland Bus Station | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Gare routière de Gerland | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Lyon Avenue Tony Garnier | Rome Tiburtina Bus Station | No tags |
Last refresh of the prices: Last Friday at 11:49 PM CEST.
Compare 2 ways to go from Lyon to Rome
Among the sustainable travel choices, the Bus stands out as a good way to reach Rome. The journey takes about 17 hours 5 minutes and with fares starting at just $33, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lyon and Rome?
Stops in Lyon
- B
Perrache
Rue de Esplanade, 69002 Lyon, France - C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - F
Les Charrières
Les Charrières, 69570 Dardilly, France
Stops in Rome
- B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
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Frequently asked questions about traveling from Lyon to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lyon to Rome?
The cheapest bus tickets from Lyon to Rome start from $33. The average price for this route is around $94. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lyon to Rome?
The average bus trip duration from Lyon to Rome is 17h 5m, covering a distance of 461 miles (744 km). The quickest bus can get you there in 13h 40m and is operated by FlixBus.
Which bus companies service the Lyon to Rome route?
Several major bus companies operate on this route with 18 buses available per day, including services from FlixBus, Itabus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Lyon to Rome?
The earliest bus departs from Lyon to Rome at 12:05am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Lyon to Rome?
A bus trip from Lyon to Rome generates an estimated 18.5887 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Lyon to Rome?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1079 reviews.
Which bus company has the best Wi-Fi from Lyon to Rome?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.9.
Which bus company has the most timely service from Lyon to Rome?
According to Busbud traveler reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Lyon to Rome?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lyon to Rome was searched and found on Jun 15, 2026 with a price of $30To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Rome, as early as possible.
You can expect to pay from $30 to $195 for a bus ticket from Lyon to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $30 which is on 2026-06-15.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
