Last refresh of the prices: Yesterday at 8:37 PM CET.
Compare 3 ways to go from Lyon to Rome
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Rome. The journey takes about 10 hours 50 minutes and with fares starting at just $77, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 944 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $35
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the departure location and the value for money but often complained with the wifi. RegioJet ticket prices on this trip start at $173
Based on 11139 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $49
Frequently asked questions about traveling from Lyon to Rome by bus
What is the distance between Lyon and Rome?
Lyon and Rome are 464 miles (748 km) apart.
What are the departure and arrival stations when taking the bus from Lyon to Rome?
If you're headed to Rome from Lyon, chances are that your bus will depart from Lyon Airport and arrive at Rome Ciampino Airport. These are the most popular departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Rome?
Once in Rome, you can start exploring the city and discover its surroundings. The top sights and things to do are Museo di Roma, Galleria Borghese, Forum Romanum, Domus Aurea – Nero’s Golden House and Cooking Classes and Food Tours in Rome.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$53
11/18
$82
Today
$66
11/20
$54
11/21
$47
11/22
$53
11/23
$47
11/24
$47
The cheapest trip from Lyon to Rome was searched and found on Nov 21, 2025 with a price of $47
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Rome, as early as possible.
You can expect to pay from $47 to $183 for a bus ticket from Lyon to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $47 which is on 2025-11-21.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Lyon to Rome was searched and found on Nov 21, 2025 with a price of $47
