Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Madisonville, USA | Louisville, KY | CheapestFastest |
Last refresh of the prices: Today at 5:55 AM CST.
Get from Madisonville to Louisville
The journey takes about 5 hours 35 minutes and with fares starting at just $107, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Madisonville to Louisville by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Madisonville to Louisville?
The cheapest bus tickets from Madisonville to Louisville start from $107. The average price for this route is around $151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Madisonville to Louisville?
The average bus trip duration from Madisonville to Louisville is 5h 35m, covering a distance of 115 miles (185 km). The quickest bus can get you there in 5h 35m and is operated by Greyhound.
Which bus companies service the Madisonville to Louisville route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Madisonville to Louisville?
The earliest bus departs from Madisonville to Louisville at 6:55pm. And the latest bus departs at 6:55pm.
What are the CO₂ emissions for the bus trip from Madisonville to Louisville?
A bus trip from Madisonville to Louisville generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Madisonville to Louisville was searched and found on Dec 11, 2025 with a price of $153To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madisonville to Louisville, as early as possible.
You can expect to pay from $153 to $153 for a bus ticket from Madisonville to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $153 which is on 2025-12-11.
Top traveled bus routes
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