Compare 3 ways to go from Mainz to Prague.
Busbud recommends carpooling from Mainz to PragueAmong the sustainable travel choices, the carpool stands out as the good way to reach Prague. The journey takes about 5 hours 10 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.
Bus Mainz to Prague: Trip Overview
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Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Mainz to Prague Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mainz to Prague.
We make it our job to connect you with the most dependable bus companies that cover bus service from Mainz to Prague.
From cheap bus tickets to more luxurious buses traveling from Mainz to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Mainz and Prague?
Frequently asked questions for your trip Mainz - Prague
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mainz to Prague was searched and found on May 19, 2025 with a price of $24To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mainz to Prague, as early as possible.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mainz to Prague but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Mainz to Prague.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mainz to Prague that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mainz to Prague.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
What's the cheapest way to go from Mainz to Prague?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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The Best Way To Book Bus and Train Tickets
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.