Bus Tickets from Panamá to São Paulo

The best way to travel from Panamá to São Paulo is by bus. Traveling by bus offers a budget-friendly, secure, and easy way to go between the two cities. Alternatively, you can also use carpooling services.

Traveling from Panamá to São Paulo takes around 16h 5m on average, although the fastest bus will take 13h 20m, on average. This is the time it takes to travel the 410 miles (662 km) that separate the two cities.

Panamá and São Paulo are 410 miles (662 km) apart.

The majority of buses traveling from Panamá to São Paulo start their journey at Fazenda Panamá Onibus and wind up at Barra Funda. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

The cheapest way to travel this route is by bus. With prices starting at $45, you won't find a more affordable way to get there.

The bus ticket costs $45 on average. Over the last 30 days, the prices ranged between $45 and $49, so make sure to compare them to get the best option.

Once in São Paulo, you can start exploring the city and discover its surroundings. The top sights and things to do are Catedral da Sé, Memorial da America Latina, Casa das Rosas, Edifício Copan and Pedra Grande - Big Stone Cliff.

Yes, it is possible to take an overnight bus from Panamá to São Paulo. Don't forget to bring a snack and a blanket to help you stay comfortable through the night.