Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Prague (Central Bus Station Florenc) | Lugano | Cheapest | ||||
| Bus | Prague (Main Station - parking) | Lugano | Fastest | ||||
| Bus | Prague (Central Bus Station Florenc) | Lugano | No tags | ||||
| Bus | Prague (Main Station - parking) | Lugano | No tags | ||||
| Bus | Černý Most | Lugano | No tags |
Last refresh of the prices: Last Thursday at 2:31 PM CET.
Get from Prague to Lugano
The journey takes about 12 hours 45 minutes and with fares starting at just $53, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Lugano?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- B
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - CChlumecká, 198 00 Praha 20, Czech Republic
- DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- EKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Lugano
- AVia Giacomo E Filippo Ciani, 6900 Lugano, Switzerland
- B
Stazione/Gare de Lugano
Stazione FFS 1, 6900 Lugano, Switzerland - C
Via Basilea
Via Basilea, 6900 Lugano, Switzerland
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Frequently asked questions about traveling from Prague to Lugano by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Lugano?
The cheapest bus tickets from Prague to Lugano start from $53. The average price for this route is around $68. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Lugano?
The average bus trip duration from Prague to Lugano is 12h 45m, covering a distance of 377 miles (608 km). The quickest bus can get you there in 11h 5m and is operated by FlixBus.
Which bus companies service the Prague to Lugano route?
What is the earliest and latest departure time for the bus from Prague to Lugano?
The earliest bus departs from Prague to Lugano at 7:00am. And the latest bus departs at 11:00pm.
What are the CO₂ emissions for the bus trip from Prague to Lugano?
A bus trip from Prague to Lugano generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Prague to Lugano?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.
Which bus company has the best Wi-Fi from Prague to Lugano?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Prague to Lugano?
According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Lugano?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Lugano was searched and found on Dec 24, 2025 with a price of $83To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Lugano, as early as possible.
