Next bus departures

Next departures for St. Louis to Cincinnati on October 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	11:45pm	Gateway Station	16h 40m	5:25pm	Cincinnati Bus Station	Cheapest
	Bus Wifi Toilet Power outlets	2:00am	Gateway Station	10h 15m	1:15pm	Cincinnati Bus Station	Fastest
	Bus Wifi Toilet Power outlets	2:05pm	Gateway Station	13h	4:05am	Cincinnati Bus Station	No tags
	Bus Wifi Toilet Power outlets	11:30pm	Gateway Station	13h 35m	2:05pm	Cincinnati (Downtown)	No tags
	Bus Wifi Toilet Power outlets	11:30pm	Gateway Station	13h 55m	2:25pm	Cincinnati (University of Cincinnati)	No tags

Last refresh of the prices: 10/11/2026 CDT.

Compare 2 ways to go from St. Louis to Cincinnati

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Cincinnati. The journey takes about 13 hours and with fares starting at just $50, it presents an excellent value for a comfortable ride.

7bus per day

13hAverage Duration

310 milesDistance

12kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$50 - $113	Average Duration13h	CO₂ emissions 12kg CO₂e
Train	Average Price$139 - $639	Average Duration18h 17m	CO₂ emissions 45kg CO₂e

Bus stations and stops in St. Louis and Cincinnati

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Stops in Cincinnati

A
Greyhound Station
1005 Gilbert Ave, Cincinnati, OH 45202
Visit page
B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA

Compare bus companies

FlixBus

3.5/516,289 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/588,240 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound St. Louis Cincinnati recent customer reviews

My original bus showed up 40 minutes late, so when I arrived to my transfer station the next bus had already left and I spent 8 more hours on buses than I should have.

Makayla H.

March 13, 2018

US bus companies:FlixBus, Greyhound, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit, Wanda Coach

Frequently asked questions about traveling from St. Louis to Cincinnati by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from St. Louis to Cincinnati?
The cheapest bus tickets from St. Louis to Cincinnati start from $50. The average price for this route is around $67. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Cincinnati?
The average bus trip duration from St. Louis to Cincinnati is 13h, covering a distance of 310 miles (499 km). The quickest bus can get you there in 10h 15m and is operated by Greyhound.
Which bus companies service the St. Louis to Cincinnati route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from St. Louis to Cincinnati?
The earliest bus departs from St. Louis to Cincinnati at 2:00am. And the latest bus departs at 11:45pm.
What are the CO₂ emissions for the bus trip from St. Louis to Cincinnati?
A bus trip from St. Louis to Cincinnati generates an estimated 12.460724999999998 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from St. Louis to Cincinnati?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 16115 reviews.
Which bus company has the best Wi-Fi from St. Louis to Cincinnati?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from St. Louis to Cincinnati?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Cincinnati?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

10/16

$63

10/17

$95

Today

$57

10/19

No data

10/20

$46

10/21

$48

10/22

$53

10/23

$55

The cheapest trip from St. Louis to Cincinnati was searched and found on Oct 20, 2026 with a price of $46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Cincinnati, as early as possible.

You can expect to pay from $46 to $102 for a bus ticket from St. Louis to Cincinnati based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2026-10-20.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.