What is the distance between Tuskegee and Chicago?

About 660 miles (1064 km) separate Tuskegee and Chicago.

What are the best sights and things to do in Chicago?

Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are The Field Museum, Lincoln Park Zoo, Museum of Contemporary Art, Museum of Science and Industry and Willis Tower (Sears Tower).

Bus Tuskegee to Chicago from $194 | Refundable Tickets

Next bus departures

Next departures for Tuskegee to Chicago on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	6:20pm	Tuskegee Bus Stop	21h 35m	3:55pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	6:20pm	Tuskegee Bus Stop	20h 55m	3:15pm	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	12:25pm	Tuskegee Bus Stop	23h 5m	11:30am	Downtown Greyhound Station	No tags
	Bus	12:25pm	Tuskegee Bus Stop	1d 1h	2:10pm	537-517 W. Jackson Blvd	No tags
	Bus	6:20pm	Tuskegee Bus Stop	1d 13h	7:50am	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Yesterday at 1:08 AM CST.

Get from Tuskegee to Chicago

This route is served by bus only

The journey takes about 22 hours 40 minutes and with fares starting at just $119, it presents an excellent value for a comfortable ride.

9bus per day

22h 40mAverage Duration

650 milesDistance

26kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,380 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Tuskegee to Chicago by bus

What is the distance between Tuskegee and Chicago?
What are the best sights and things to do in Chicago?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/16

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11/17

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Today

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11/19

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11/20

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11/21

$194

11/22

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11/23

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The cheapest trip from Tuskegee to Chicago was searched and found on Nov 21, 2025 with a price of $194

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tuskegee to Chicago, as early as possible.

You can expect to pay from $194 to $225 for a bus ticket from Tuskegee to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $194 which is on 2025-11-21.