Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Wytheville Bus Station | Roanoke Bus Stop | No tags | ||||
| Bus | Wytheville Bus Station | Roanoke Bus Stop | No tags | ||||
| Bus | Wytheville Bus Station | Roanoke Bus Stop | No tags | ||||
| Bus | Wytheville Bus Station | Roanoke Bus Stop | No tags | ||||
| Bus | Wytheville Bus Station | Roanoke Bus Stop | No tags |
Get from Wytheville to Roanoke
The journey takes about 1 hour 5 minutes and with fares starting at just $22, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Wytheville to Roanoke by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wytheville to Roanoke was searched and found on Nov 19, 2025 with a price of $14To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wytheville to Roanoke, as early as possible.
Top traveled bus routes
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