Train from Greenville, SC to Boston, MA, US: Tickets & Schedules

Next train departures

Next departures for Greenville to Boston on February 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Greenville Station
South Station (Train Terminal)Cheapest
AmtrakTrain
Greenville Station
Boston Route 128, MAFastest
AmtrakTrain
Greenville Station
South Station (Train Terminal)No tags
AmtrakTrain
Greenville Station
South Station (Train Terminal)No tags
AmtrakTrain
Greenville Station
Back Bay StationNo tags

Last refresh of the prices: Last Wednesday at 5:21 PM EST.

Compare 2 ways to go from Greenville to Boston

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Boston. The journey takes about 22 hours 55 minutes and with fares starting at just $80, it presents an excellent value for a comfortable ride.

9bus per day
22h 55mAverage Duration
797 milesDistance
32kgCO₂ emissions
Average Price$80 - $268Average Duration22h 55m
32kg CO₂e
Average Price$176 - $727Average Duration21h 35m
117kg CO₂e

Frequently asked questions about traveling from Greenville, SC to Boston, MA, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Greenville to Boston?

    The cheapest train tickets from Greenville to Boston start from $176. The average price for this train route is around $359. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the train journey from Greenville to Boston?

    The average train ride duration from Greenville to Boston is 21h 35m, covering a distance of 800 miles (1290 km). The quickest train can get you there in 21h 35m and is operated by Amtrak.

  3. Which train operators service the Greenville to Boston route?

    Several major train operators operate on this route with 4 trains available per day.

  4. What is the earliest and latest departure time for the train from Greenville to Boston?

    The earliest train departs from Greenville to Boston at 2:23am. And the latest train departs at 2:23am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/29
$296
01/30
$315
Today
No data
02/01
No data
02/02
$245
02/03
$168
02/04
$245
02/05
No data
busbud logoThe cheapest trip from Greenville, SC to Boston, MA, US was searched and found on Feb 3, 2026 with a price of $168

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Boston, MA, US, as early as possible.

You can expect to pay from $168 to $780 for a train ticket from Greenville, SC to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $168 which is on 2026-02-03.

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