Compare 2 ways to go from Cleveland to Florence.
Busbud recommends taking the bus from Cleveland to FlorenceAmong the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 20 hours and with fares starting at just $145, it presents an excellent value for a comfortable ride.
Train Cleveland, OH, US to Florence, SC, US: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5317 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $348
Cleveland to Florence Train
With Busbud, comparing and booking tickets for a train from Cleveland to Florence is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make sure you can find a train service from Cleveland to Florence from the most reliable train companies operating this trip.
From train tickets to high-end trains trip from Cleveland to Florence, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Cleveland, OH, US - Florence, SC, US
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Cleveland to Florence was searched and found on Jul 21, 2025 with a price of $417To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Cleveland to Florence, as early as possible.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Cleveland to Florence is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Regional train? High-speed train? Whichever train to Florence you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between Cleveland and Florence compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Tune out to the fine sounds of your best music playlist on your train trip from Cleveland to Florence while indulging in miles on end of beautiful scenic views.
Did you know?
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
Top Traveled Train Routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Trains Connecting Cleveland
Trains Leaving from Cleveland
Popular Trains Connecting Florence
Trains Going to Florence
Popular train trips
Top Routes Worldwide
- Train from Wells to Fargo
- Train from Richmond to Richmond
- Train from Columbia to New York City
- Train from Detroit to Red Wing
- Train from Los Angeles to Glendale
- Train from Waterloo to Buffalo
- Train from Washington to Leavenworth
- Train from Niagara Falls to Ontario
- Train from Washington to Everett
- Train from Buffalo to New York City
- Train from Seattle to Washington
- Train from Rochester to New York City
- Train from Jacksonville to Jacksonville
- Train from Ventura to Simi Valley
- Train from Fayetteville to Cumberland