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| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Intermodal Station | Greenville Station | No tags | |||||
| MKE Airport - Trains | Greenville Station | No tags | |||||
| Intermodal Station | Greenville Station | No tags | |||||
| MKE Airport - Trains | Greenville Station | No tags | |||||
| Intermodal Station | Greenville Station | No tags |
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Compare 2 ways to go from Milwaukee to Greenville
Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 1 day, 3 hours 40 minutes and with fares starting at just $147, it presents an excellent value for a comfortable ride.
Train Milwaukee to Greenville, SC: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5564 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $376
Milwaukee to Greenville Train
With Busbud, comparing and booking tickets for a train from Milwaukee to Greenville is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
Train service from Milwaukee to Greenville will be provided by the most trusted companies.
Discover how much the train trip from Milwaukee to Greenville will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.
Frequently asked questions for your trip Milwaukee - Greenville, SC
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milwaukee to Greenville, SC was searched and found on Nov 3, 2025 with a price of $325To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Milwaukee to Greenville, SC, as early as possible.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Milwaukee to Greenville is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
No matter if you plan to take a regional or high-speed train to Greenville, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
With up to 30x less CO2 emissions for your train journey between Milwaukee and Greenville, the train is an ecological alternative to flights or personal cars.
Tune out to the fine sounds of your best music playlist on your train trip from Milwaukee to Greenville while indulging in miles on end of beautiful scenic views.
Did you know?
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date
Top Traveled Train Routes
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