Bus Tickets from Milwaukee to Greenville, SC

Previously seen trips

Next departures for Milwaukee to Greenville on November 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
    		Milwaukee Bus Station, St. Paul & N6th road.
    		1116 Woodruff RdNo tags
    FlixBus + Greyhound
      		Milwaukee Bus Station, St. Paul & N6th road.
      		1116 Woodruff RdNo tags
      Greyhound + FlixBus
        		Goerke's Corners Park & Ride (Brookfield)
        		1116 Woodruff RdNo tags
        FlixBus + Greyhound
          		Goerke's Corners Park & Ride (Brookfield)
          		1116 Woodruff RdNo tags
          Greyhound + FlixBus
            		Milwaukee (Downtown)
            		1116 Woodruff RdNo tags

            Accepted payments

            • Visa
            • MasterCard
            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Compare 2 ways to go from Milwaukee to Greenville

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 1 day, 3 hours 40 minutes and with fares starting at just $147, it presents an excellent value for a comfortable ride.

            7bus per day
            1d 3hAverage Duration
            635 milesDistance
            26kgCO₂ emissions
            Bus
            		Average Price$147 - $379Average Duration1d 3h
            26kg CO₂e
            Train
            		Average Price$376 - $376Average Duration1d 13h
            93kg CO₂e

            Bus Milwaukee to Greenville, SC: Trip Overview

            Average ticket price$148
            Average bus trip duration1d 3h
            Number of daily buses7
            Earliest bus departure6:30am
            Distance635 miles (1024 km)
            Latest bus departure3:40pm

            Milwaukee to Greenville Bus

            With Busbud, comparing and booking tickets for a bus from Milwaukee to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            Bus service from Milwaukee to Greenville will be provided by the most trusted bus companies.

            Discover how much the bus trip from Milwaukee to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

            Frequently asked questions for your trip Milwaukee - Greenville, SC

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11/02
            No data
            11/03
            $180
            Today
            No data
            11/05
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            11/06
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            11/07
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            11/08
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            11/09
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            busbud logoThe cheapest trip from Milwaukee to Greenville, SC was searched and found on Nov 3, 2025 with a price of $180

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to Greenville, SC, as early as possible.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while traveling from Milwaukee to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Much more than a mere vehicle taking you from Milwaukee to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milwaukee to Greenville will emit less CO2 than a car or an airplane.

            Tune out to the fine sounds of your best music playlist on your bus trip from Milwaukee to Greenville while indulging in miles on end of beautiful scenic views.

            Did you know?

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            What's the cheapest way to go from Milwaukee to Greenville, SC?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Milwaukee by bus?

            Bus from Greenville, SC to Milwaukee

            You can also go to Greenville, SC by train

            Train from Milwaukee to Greenville, SC

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