Next departures to Jacksonville
One passenger / one way
- This trip is recommended because it is: CheapestDeparture time: June 28 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 30 atDestination city: JacksonvilleDestination location: Jacksonville Amtrak StationOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is: FastestDeparture time: June 28 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 30 atDestination city: JacksonvilleDestination location: Jacksonville Amtrak StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 28 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 30 atDestination city: JacksonvilleDestination location: Jacksonville Amtrak StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 28 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 30 atDestination city: JacksonvilleDestination location: Jacksonville Amtrak StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 28 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 30 atDestination city: JacksonvilleDestination location: Jacksonville Amtrak StationOperated by: AmtrakVehicle: BusDuration:
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Compare 2 ways to go from St Louis to Jacksonville.
Busbud recommends taking the bus from St Louis to JacksonvilleAmong the sustainable travel choices, the bus stands out as the good way to reach Jacksonville. The journey takes about 22 hours and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Train St Louis to Jacksonville: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5233 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $161
St Louis to Jacksonville Train
With Busbud, comparing and booking tickets for a train from St Louis to Jacksonville is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make it our job to connect you with the most dependable companies that offer train service from St Louis to Jacksonville.
From train tickets to high-end trains trip from St Louis to Jacksonville, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Where are the popular train stations and stops in St Louis and Jacksonville, FL?
Frequently asked questions for your trip St Louis - Jacksonville, FL
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St Louis to Jacksonville was searched and found on Jun 23, 2025 with a price of $329To save money and be sure you have the best seat, it's a good idea to buy your train tickets from St Louis to Jacksonville, as early as possible.
You can expect to pay from $329 to $1,909 for a train ticket from St Louis to Jacksonville based on the last 2 days. You can expect to find the cheapest price for the trip at $470 which is on 2025-06-28.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from St Louis to Jacksonville is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Whether you take a regional or high-speed train to Jacksonville, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between St Louis and Jacksonville compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from St Louis to Jacksonville.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.
Top Traveled Train Routes
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Trains Leaving from St Louis
Popular Trains Connecting Jacksonville
Trains Going to Jacksonville
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