How much does a train ticket from St. Louis to Buffalo cost?

The average train ticket price from St. Louis to Buffalo is $163. The best way to find train tickets from St. Louis to Buffalo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the train trip from St. Louis to Buffalo?

A train trip between St. Louis and Buffalo is around 16h 58m, although the fastest train will take about 16h 58m. This is the time it takes to travel the 660 miles that separates the two cities.

How many daily trains are there between St. Louis and Buffalo?

The number of trains from St. Louis to Buffalo can differ depending on the day of the week. On average, there are 2. Some trains are direct while others have layovers. Simplify your train trip from St. Louis to Buffalo by comparing and selecting the train that fits your travel style and budget on Busbud.

Which train companies travel from St. Louis to Buffalo?

When taking the train from St. Louis to Buffalo, you can travel comfortably and safely with Amtrak.

Train St. Louis to Buffalo from $156 | Refundable Tickets

Previously seen trips

Next departures for St. Louis to Buffalo on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	8:10am	Gateway Station	23h 43m	8:53am	Depew Station	No tags
Train	8:10am	Gateway Station	23h 43m	8:53am	Depew Station	No tags
Train	8:10am	Gateway Station	23h 43m	9:53am	Depew Station	No tags
Train	8:10am	Gateway Station	23h 43m	8:53am	Depew Station	No tags
Train	8:55am	Gateway Station	22h 58m	8:53am	Depew Station	No tags

Compare 2 ways to go from St. Louis to Buffalo

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Buffalo. The journey takes about 16 hours 58 minutes and with fares starting at just $126, it presents an excellent value for a comfortable ride.

2train per day

16h 58mAverage Duration

668 milesDistance

98kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$75 - $254	Average Duration1d 8h	CO₂ emissions 27kg CO₂e
Train	Average Price$126 - $962	Average Duration16h 58m	CO₂ emissions 98kg CO₂e

Where are the popular train stations and stops in St. Louis and Buffalo, NY?

St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Buffalo, NY

A
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Train Companies

Amtrak

4/55,600 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5600 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $126

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from St. Louis to Buffalo, NY by train

How much does a train ticket from St. Louis to Buffalo cost?
How long is the train trip from St. Louis to Buffalo?
How many daily trains are there between St. Louis and Buffalo?
Which train companies travel from St. Louis to Buffalo?

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/21

No data

11/22

No data

Today

No data

11/24

No data

11/25

$282

11/26

No data

11/27

No data

11/28

$282

The cheapest trip from St. Louis to Buffalo, NY was searched and found on Nov 25, 2025 with a price of $282

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from St. Louis to Buffalo, NY, as early as possible.

You can expect to pay from $282 to $928 for a train ticket from St. Louis to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $282 which is on 2025-11-25.