Trains tickets from Buffalo (NY) to Chicago

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TodayMay 1
TomorrowMay 2
from $152
SatMay 3
from $152
SunMay 4
MonMay 5
TueMay 6
WedMay 7
ThuMay 8

Trains leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 2 at
    Departure city: Buffalo
    Departure location: Depew Station
    Arrival time: May 2 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: May 2 at
    Departure city: Buffalo
    Departure location: Depew Station
    Arrival time: May 2 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to go from Buffalo to Chicago.

Bus
Average Price$55 - $166Average Duration18h 20m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$88 - $187Average Duration10h 33m
67kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Buffalo to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 18 hours 20 minutes and with fares starting at just $55, it presents an excellent value for a comfortable ride.

5bus per day
18h 20mAverage Duration
$55Cheapest ticket
18kgCO₂ emissions

Train Buffalo to Chicago: Trip Overview

Please note, this information is subject to change.

Average ticket price$111
Average train trip duration10h 33m
Number of daily trains1
Earliest train departure12:39am
Distance460 miles (741 km)

Buffalo to Chicago Train

Busbud helps you find a train from Buffalo to Chicago. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.

We make sure you can find a train service from Buffalo to Chicago from the most reliable train companies operating this trip.

From train tickets to high-end trains trip from Buffalo to Chicago, we offer a wide range of train services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Buffalo - Chicago

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/29
$125
04/30
$125
Today
No data
05/02
$152
05/03
$152
05/04
No data
05/05
$103
05/06
$103
busbud logoThe cheapest trip from Buffalo to Chicago was searched and found on May 5, 2025 with a price of $103

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo to Chicago, as early as possible.

You can expect to pay from $103 to $584 for a train ticket from Buffalo to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $103 which is on 2025-05-05.

About Train Travel

Train Travel Tips

There are many train stations in the world, check it station pages on Busbud to get all information you need.

Regional train? High-speed train? Whichever train to Chicago you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

The train emits up to 30x less CO2 for a trip between Buffalo and Chicago compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.

Make a music playlist for your train ride from Buffalo to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.

The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.

You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.

Will you be returning to Buffalo by train?

Train from Chicago to Buffalo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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