Trains leaving Friday
One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: June 27 atDeparture city: WilmingtonDeparture location: Wilmington StationArrival time: June 28 atDestination city: St LouisDestination location: Gateway StationOperated by: Amtrak
Vehicle: TrainDuration: - Departure time: June 27 atDeparture city: WilmingtonDeparture location: Wilmington StationArrival time: June 28 atDestination city: St LouisDestination location: Gateway StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 27 atDeparture city: WilmingtonDeparture location: Wilmington StationArrival time: June 28 atDestination city: St LouisDestination location: Gateway StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 27 atDeparture city: WilmingtonDeparture location: Wilmington StationArrival time: June 28 atDestination city: St LouisDestination location: Gateway StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 27 atDeparture city: WilmingtonDeparture location: Wilmington StationArrival time: June 28 atDestination city: St LouisDestination location: Gateway StationOperated by: AmtrakVehicle: TrainDuration:
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Compare 2 ways to go from Wilmington to St Louis.
Busbud recommends taking the bus from Wilmington to St LouisAmong the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just $115, it presents an excellent value for a comfortable ride.
Train Wilmington to St Louis: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5224 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $335
Wilmington to St Louis Train
Busbud helps you find a train from Wilmington to St Louis. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
Train service from Wilmington to St Louis will be provided by the most trusted companies.
Whether it is train tickets or first class train tickets going to St Louis from Wilmington, we help you find what you're looking for based on how much of a budget you have.
Where are the popular train stations and stops in Wilmington, DE and St Louis?
Frequently asked questions for your trip Wilmington, DE - St Louis
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington to St Louis was searched and found on Jun 22, 2025 with a price of $322To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Wilmington to St Louis, as early as possible.
You can expect to pay from $322 to $1,728 for a train ticket from Wilmington to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $473 which is on 2025-06-27.
About Train Travel
Train Travel Tips
There are many train stations in the world, check it station pages on Busbud to get all information you need.
No matter if you plan to take a regional or high-speed train to St Louis, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
By choosing the train between Wilmington and St Louis, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Tune out to the fine sounds of your best music playlist on your train trip from Wilmington to St Louis while indulging in miles on end of beautiful scenic views.
Did you know?
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
Top Traveled Train Routes
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Popular Trains Connecting Wilmington
Trains Leaving from Wilmington
Popular Trains Connecting St Louis
Trains Going to St Louis
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