Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Niagara Frontier Transportation Authority | 1116 Woodruff Rd | No tags | ||||
| Bus | Buffalo (BUF) Airport | 1116 Woodruff Rd | No tags | ||||
| Bus | Niagara Frontier Transportation Authority | 1116 Woodruff Rd | No tags | ||||
Greyhound + FlixBus | Bus | Niagara Frontier Transportation Authority | 1116 Woodruff Rd | No tags | ||||
| Bus | Buffalo (BUF) Airport | 1116 Woodruff Rd | No tags |
Compare 2 ways to go from Buffalo to Greenville
Among the sustainable travel choices, the Train stands out as a good way to reach Greenville. The journey takes about 1 day, 56 minutes, and with fares starting at just $307, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$155 - $531 | Average Duration1d 2h | 24kg CO₂e | ||
Train | Average Price$307 - $565 | Average Duration1d | 86kg CO₂e |
Where are the popular stops in Buffalo and Greenville?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Compare bus companies
Frequently asked questions about travelling from Buffalo, NY to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Buffalo to Greenville?
The cheapest bus tickets from Buffalo to Greenville start from $155. The average price for this route is around $270. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Buffalo to Greenville?
The average bus travel time from Buffalo to Greenville is 1d 2h, covering a distance of 944 km. The quickest bus can get you there in 1d and is operated by FlixBus.
Which bus companies service the Buffalo to Greenville route?
What are the earliest and latest departure times for the bus from Buffalo to Greenville?
The earliest bus departs from Buffalo to Greenville at 12:55am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Buffalo to Greenville?
A bus trip from Buffalo to Greenville generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Buffalo to Greenville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12050 reviews.
Which bus company has the best Wi-Fi from Buffalo to Greenville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Buffalo to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Greenville, SC was searched and found on Jan 18, 2026 with a price of $184To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Greenville, SC, as early as possible.
What's the cheapest way to go from Buffalo, NY to Greenville, SC?
The Bus is the cheapest travel choice for this destination
