Bus from Charleston, SC, US to Jacksonville, FL: Tickets & Schedules

Next bus departures

Next departures for Charleston to Jacksonville on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Jacksonville Bus StationCheapestFastest

Last refresh of the prices: Today at 1:44 PM EST.

Compare 2 ways to go from Charleston to Jacksonville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Jacksonville. The journey takes about 9 hours 50 minutes, and with fares starting at just $50, it presents an excellent value for a comfortable ride.

2bus per day
9h 50mAverage Duration
325 kmDistance
8kgCO₂ emissions
Average Price$50 - $127Average Duration9h 50m
8kg CO₂e
Average Price$74 - $220Average Duration10h 55m
29kg CO₂e

Frequently asked questions about travelling from Charleston, SC, US to Jacksonville, FL by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Charleston to Jacksonville?

    The cheapest bus tickets from Charleston to Jacksonville start from $50. The average price for this route is around $74. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Charleston to Jacksonville?

    The average bus travel time from Charleston to Jacksonville is 9h 50m, covering a distance of 325 km. The quickest bus can get you there in 5h 5m and is operated by FlixBus.

  3. Which bus companies service the Charleston to Jacksonville route?

    Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, Greyhound.

  4. What are the earliest and latest departure times for the bus from Charleston to Jacksonville?

    The earliest bus departs from Charleston to Jacksonville at 11:15am. And the latest bus departs at 3:15pm.

  5. What are the CO₂ emissions for the bus trip from Charleston to Jacksonville?

    A bus trip from Charleston to Jacksonville generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Charleston to Jacksonville?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from Charleston to Jacksonville?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Charleston to Jacksonville?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Charleston to Jacksonville?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-25
$70
11-26
$81
Today
$72
11-28
$68
11-29
$70
11-30
$81
12-01
$72
12-02
$64
busbud logoThe cheapest trip from Charleston, SC, US to Jacksonville, FL was searched and found on Dec 2, 2025 with a price of $64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Jacksonville, FL, as early as possible.

You can expect to pay from $64 to $81 for a bus ticket from Charleston, SC, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $64 which is on 2025-12-02.

What's the cheapest way to go from Charleston, SC, US to Jacksonville, FL?

busbud logoThe bus is the cheapest travel choice for this destination

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