Next departures for Charleston to Orlando on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
CheapestFastest
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Next departures for Charleston to Orlando on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
CheapestFastest
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Next departures for Charleston to Orlando on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
CheapestFastest
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Next departures for Charleston to Orlando on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
CheapestFastest
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Next departures for Charleston to Orlando on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
CheapestFastest
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Next departures for Charleston to Orlando on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
CheapestFastest
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Next departures for Charleston to Orlando on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
Fastest
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Next departures for Charleston to Orlando on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
CheapestFastest
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Orlando Bus Station
No tags
Last refresh of the prices: Yesterday at 10:28 PM EST.
Compare 2 ways to go from Charleston to Orlando
We recommend taking the train
Among the sustainable travel choices, the train stands out as a good way to reach Orlando. The journey takes about 8 hours 8 minutes, and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Based on 87387 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $81
Based on 11388 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $72
Frequently asked questions about travelling from Charleston, SC, US to Orlando by bus
How far is Charleston from Orlando?
It's about 493 km (306 miles) from Charleston to Orlando.
What are the departure and arrival locations for buses traveling from Charleston to Orlando?
Buses traveling this route start their trip at Charleston Bus Station, in Charleston, and end it at Orlando Bus Station, in Orlando.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-19
$194
11-20
$284
Today
$258
11-22
$248
11-23
$209
11-24
$256
11-25
$188
11-26
$190
The cheapest trip from Charleston, SC, US to Orlando was searched and found on Nov 25, 2025 with a price of $188
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Orlando, as early as possible.
You can expect to pay from $188 to $284 for a bus ticket from Charleston, SC, US to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $188 which is on 2025-11-25.
What's the cheapest way to go from Charleston, SC, US to Orlando?
The bus is the cheapest travel choice for this destination
The cheapest trip from Charleston, SC, US to Orlando was searched and found on Nov 25, 2025 with a price of $188
The bus is the cheapest travel choice for this destination
