Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Charleston Bus Station | San Diego (Old Town-FlixBus) | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Charleston Bus Station | UCSD Health La Jolla Station | Fastest | ||||
 | Bus | Charleston Bus Station | Greyhound Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Charleston Bus Station | Downtown SD (Seaport) | No tags |
Last refresh of the prices: Last Thursday at 5:27 PM EST.
Compare 2 ways to go from Charleston to San Diego
Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 11 hours 55 minutes, and with fares starting at just $379, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charleston and San Diego?
Stops in Charleston
- A
Charleston Greyhound Bus Station
300 Reynolds St, Charleston, WV 25301 - B
Slack Plaza Charleston Transit Mall
154-168 Laidley St, Charleston, WV 25301, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Based on 87431 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $379
Frequently asked questions about travelling from Charleston, WV, US to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Charleston to San Diego?
The cheapest bus tickets from Charleston to San Diego start from $379. The average price for this route is around $506. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charleston to San Diego?
The average bus travel time from Charleston to San Diego is 2d 11h, covering a distance of 3256 km. The quickest bus can get you there in 2d 11h and is operated by Greyhound.
Which bus companies service the Charleston to San Diego route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Charleston to San Diego?
The earliest bus departs from Charleston to San Diego at 9:15am. And the latest bus departs at 9:15am.
What are the CO₂ emissions for the bus trip from Charleston to San Diego?
A bus trip from Charleston to San Diego generates an estimated 81 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, WV, US to San Diego, CA, US was searched and found on Dec 14, 2025 with a price of $381To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, WV, US to San Diego, CA, US, as early as possible.
You can expect to pay from $381 to $532 for a bus ticket from Charleston, WV, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $507 which is on 2025-12-15.
What's the cheapest way to go from Charleston, WV, US to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
