How much is the bus ticket from Charleston to San Diego?

The cheapest bus tickets from Charleston to San Diego start from $269. The average price for this route is around $358. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Charleston to San Diego?

The average bus trip duration from Charleston to San Diego is 2d 11h, covering a distance of 2019 miles (3256 km). The quickest bus can get you there in 2d 11h and is operated by Greyhound .

Which bus companies service the Charleston to San Diego route?

Several major train operators operate on this route with 4 trains available per day.

What is the earliest and latest departure time for the bus from Charleston to San Diego?

The earliest bus departs from Charleston to San Diego at 9:15am. And the latest bus departs at 9:15am.

What are the CO₂ emissions for the bus trip from Charleston to San Diego?

A bus trip from Charleston to San Diego generates an estimated 81 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Charleston to San Diego from $270 | Refundable Tickets

Next bus departures

Next departures for Charleston to San Diego on December 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 11h	5:35pm	UCSD Health La Jolla Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 11h	6:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	9:15am	Charleston Bus Station	2d 11h	5:45pm	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 16h	10:15pm	Downtown SD (Seaport)	No tags

Next departures for Charleston to San Diego on December 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 11h	6:10pm	San Diego (Old Town-FlixBus)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 11h	5:35pm	UCSD Health La Jolla Station	Fastest
	Bus	9:15am	Charleston Bus Station	2d 17h	11:50pm	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 16h	10:15pm	Downtown SD (Seaport)	No tags

Next departures for Charleston to San Diego on December 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 11h	6:10pm	San Diego (Old Town-FlixBus)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 11h	5:35pm	UCSD Health La Jolla Station	Fastest
	Bus	9:15am	Charleston Bus Station	2d 11h	5:45pm	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:15am	Charleston Bus Station	2d 16h	10:15pm	Downtown SD (Seaport)	No tags

Last refresh of the prices: Last Tuesday at 8:57 PM EST.

Compare 2 ways to go from Charleston to San Diego

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach San Diego. The journey takes about 2 days, 11 hours 55 minutes and with fares starting at just $269, it presents an excellent value for a comfortable ride.

4bus per day

2d 11hAverage Duration

2019 milesDistance

81kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$269 - $510	Average Duration2d 11h	CO₂ emissions 81kg CO₂e
Train	Average Price$475 - $1,439	Average Duration2d 19h	CO₂ emissions 296kg CO₂e

Where are the popular stops in Charleston and San Diego?

Stops in Charleston

A
Charleston Greyhound Bus Station
300 Reynolds St, Charleston, WV 25301
B
Slack Plaza Charleston Transit Mall
154-168 Laidley St, Charleston, WV 25301, USA

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Greyhound

3.5/587,430 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Charleston, WV, US to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Charleston to San Diego?
The cheapest bus tickets from Charleston to San Diego start from $269. The average price for this route is around $358. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charleston to San Diego?
The average bus trip duration from Charleston to San Diego is 2d 11h, covering a distance of 2019 miles (3256 km). The quickest bus can get you there in 2d 11h and is operated by Greyhound.
Which bus companies service the Charleston to San Diego route?
Several major train operators operate on this route with 4 trains available per day.
What is the earliest and latest departure time for the bus from Charleston to San Diego?
The earliest bus departs from Charleston to San Diego at 9:15am. And the latest bus departs at 9:15am.
What are the CO₂ emissions for the bus trip from Charleston to San Diego?
A bus trip from Charleston to San Diego generates an estimated 81 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/11

No data

12/12

$282

Today

No data

12/14

$270

12/15

$359

12/16

No data

12/17

$377

12/18

No data

The cheapest trip from Charleston, WV, US to San Diego, CA, US was searched and found on Dec 14, 2025 with a price of $270

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, WV, US to San Diego, CA, US, as early as possible.

You can expect to pay from $270 to $377 for a bus ticket from Charleston, WV, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $270 which is on 2025-12-14.