Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Charleston Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Charleston Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Charleston Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Charleston Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Charleston Bus Station | Winston Salem Greyhound Bus Station | No tags |
Get from Charleston to Winston-Salem
The journey takes about 4 hours 55 minutes, and with fares starting at just $61, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charleston and Winston-Salem?
Stops in Charleston
- A
Charleston Greyhound Bus Station
300 Reynolds St, Charleston, WV 25301 - B
Slack Plaza Charleston Transit Mall
154-168 Laidley St, Charleston, WV 25301, USA
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Compare bus companies
Based on 87412 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $61
Frequently asked questions about travelling from Charleston, WV, US to Winston-Salem by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Charleston to Winston-Salem?
The cheapest bus tickets from Charleston to Winston-Salem start from $61. The average price for this route is around $84. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charleston to Winston-Salem?
The average bus travel time from Charleston to Winston-Salem is 4h 55m, covering a distance of 280 km. The quickest bus can get you there in 4h 55m and is operated by Greyhound.
Which bus companies service the Charleston to Winston-Salem route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Charleston to Winston-Salem?
The earliest bus departs from Charleston to Winston-Salem at 5:20am. And the latest bus departs at 5:20am.
What are the CO₂ emissions for the bus trip from Charleston to Winston-Salem?
A bus trip from Charleston to Winston-Salem generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, WV, US to Winston-Salem was searched and found on Dec 6, 2025 with a price of $51To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, WV, US to Winston-Salem, as early as possible.
You can expect to pay from $51 to $51 for a bus ticket from Charleston, WV, US to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $51 which is on 2025-12-06.
