Based on 2115 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. Flechabus ticket prices on this trip start at $29
Based on 132 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the departure location but often complained with the WiFi. Encon ticket prices on this trip start at $35
Based on 299 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the staff and the departure location but often complained with the power outlets. Nuevo Expreso ticket prices on this trip start at $36
Río Uruguay offers 1 daily buses from Colón to Santa Fe. Though the average price for this trip is $38, you can find tickets starting at $35. The trip between the two cities usually takes about 280.
Based on 571 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the departure location and the ticket access but often complained with the WiFi. Rio Uruguay ticket prices on this trip start at $35
Frequently asked questions about travelling from Colón, Entre Rios, AR to Santa Fe, AR by bus
What is the distance between Colón and Santa Fe?
The distance between Colón and Santa Fe is approximately 251 km (156 miles).
What are the departure and arrival locations for buses traveling from Colón to Santa Fe?
Buses departing from Terminal de Omnibus Colón in Colón will take you to Estación Terminal de Ómnibius, Santa Fe in Santa Fe.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-18
No data
11-19
$35
Today
No data
11-21
No data
11-22
$33
11-23
No data
11-24
$34
11-25
$35
The cheapest trip from Colón, Entre Rios, AR to Santa Fe, AR was searched and found on Nov 22, 2025 with a price of $33
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Colón, Entre Rios, AR to Santa Fe, AR, as early as possible.
You can expect to pay from $33 to $39 for a bus ticket from Colón, Entre Rios, AR to Santa Fe, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $33 which is on 2025-11-22.
Usually Flechabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Colón, Entre Rios, AR to Santa Fe, AR was searched and found on Nov 22, 2025 with a price of $33
