Bus from Columbia, MO to Charlotte, NC: Tickets & Schedules

Previously seen trips

Next departures for Columbia to Charlotte on November 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
GreyhoundBus
Midway Truck Plaza Bus Stop
Charlotte Bus StationNo tags
FlixBus + Greyhound
Bus
Midway Truck Plaza Bus Stop
Charlotte (Freedom Dr)No tags
GreyhoundBus
Columbia Wabash Station
Charlotte Bus StationNo tags
Greyhound + FlixBus
Bus
Columbia Wabash Station
Charlotte (Freedom Dr)No tags
FlixBus + Greyhound
Bus
Columbia Wabash Station
Charlotte (Freedom Dr)No tags

Get from Columbia to Charlotte

This route is served by bus only

The journey takes about 21 hours 15 minutes, and with fares starting at just $121, it presents an excellent value for a comfortable ride.

6bus per day
21h 15mAverage Duration
1094 kmDistance
27kgCO₂ emissions

Frequently asked questions about travelling from Columbia, MO to Charlotte, NC by bus

  1. What is the distance between Columbia and Charlotte?

    It's about 1101 km (683 miles) from Columbia to Charlotte.

  2. What are the departure and arrival locations for buses traveling from Columbia to Charlotte?

    Buses traveling this route start their trip at Midway Truck Plaza Bus Stop, in Columbia, and end it at Tornado & El Expreso Bus Company, in Charlotte.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-24
$228
11-25
No data
Today
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11-27
No data
11-28
No data
11-29
No data
11-30
No data
12-01
No data
busbud logoThe cheapest trip from Columbia, MO to Charlotte, NC was searched and found on Nov 24, 2025 with a price of $228

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia, MO to Charlotte, NC, as early as possible.

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