Bus Tickets from Columbia, SC to Gainesville, FL

Next departures

Next departures for Columbia to Gainesville on October 6
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Tornado Bus + Expreso
Columbia
Williston Rd & I-75CheapestFastest

Last refresh of the prices: 2025-09-28 EDT.

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Bus Columbia, SC to Gainesville, FL: Trip Overview

Average Ticket PriceUS$279
Average Bus Trip Duration21h 35m
Number of daily buses1
Earliest bus departure12:30pm
Distance514 km

Columbia to Gainesville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Columbia to Gainesville.

We make sure you can find a bus service from Columbia to Gainesville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Gainesville from Columbia, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Columbia, SC - Gainesville, FL

  1. What is the distance between Columbia and Gainesville?

    Columbia and Gainesville are 500 km (310 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Columbia to Gainesville?

    Buses departing from Columbia Bus Station in Columbia will take you to Williston Rd & I-75 in Gainesville.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Columbia to Gainesville but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Columbia to Gainesville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Columbia to Gainesville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Columbia to Gainesville.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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