Bus Tickets from Denver to Santa Ana, US

Next departures

Next departures for Denver to Santa Ana on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
DENVER
Anaheim Regional Transportation Intermodal CenterCheapest
Greyhound Lines, Inc.
DENVER
Santa Ana Bus StationFastest

Last refresh of the prices: Yesterday at 6:50 PM MDT.

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Bus Denver to Santa Ana, US: Trip Overview

Average Ticket PriceUS$133
Average Bus Trip Duration1d 14h
Number of daily buses10
Earliest bus departure11:05am
Distance1322 km
Latest bus departure8:10pm

Denver to Santa Ana Bus

Busbud helps you find a bus from Denver to Santa Ana. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Denver to Santa Ana will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santa Ana from Denver, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Denver - Santa Ana, US

  1. What is the distance between Denver and Santa Ana?

    Denver and Santa Ana are 1327 km (823 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Denver to Santa Ana?

    Buses departing from Union Station in Denver will take you to Santa Ana Greyhound Bus Station in Santa Ana.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-11
US$108
10-12
No data
Today
US$154
10-14
No data
10-15
No data
10-16
No data
10-17
No data
10-18
No data
busbud logoThe cheapest trip from Denver to Santa Ana, US was searched and found on Oct 11, 2025 with a price of US$108

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to Santa Ana, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Denver and Santa Ana!

Much more than a mere vehicle taking you from Denver to Santa Ana, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Denver to Santa Ana.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Denver to Santa Ana.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Denver by bus?

Bus from Santa Ana, US to Denver

Why choose Busbud?

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