Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Des Moines (Subway) | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | Downtown Transit Center | No tags | ||||
Greyhound + FlixBus | Bus | Des Moines (Subway) | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | Downtown Transit Center | No tags |
Get from Des Moines to Indianapolis
The journey takes about 13 hours, and with fares starting at just $106, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Indianapolis?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
Frequently asked questions about travelling from Des Moines to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to Indianapolis?
The cheapest bus tickets from Des Moines to Indianapolis start from $106. The average price for this route is around $162. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Indianapolis?
The average bus travel time from Des Moines to Indianapolis is 13h, covering a distance of 660 km. The quickest bus can get you there in 9h 30m and is operated by Burlington Trailways.
Which bus companies service the Des Moines to Indianapolis route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, Jefferson Lines, Burlington Trailways.
What are the earliest and latest departure times for the bus from Des Moines to Indianapolis?
The earliest bus departs from Des Moines to Indianapolis at 5:30am. And the latest bus departs at 9:30am.
What are the CO₂ emissions for the bus trip from Des Moines to Indianapolis?
A bus trip from Des Moines to Indianapolis generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Des Moines to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from Des Moines to Indianapolis?
Based on Busbud reviews, the bus company Burlington Trailways has the highest Wi-Fi rating with a score of 5.0.
Which bus company has the best on-time performance from Des Moines to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Des Moines to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Indianapolis was searched and found on Dec 1, 2025 with a price of $129To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Indianapolis, as early as possible.
