Bus Tickets from Des Moines to Philadelphia, PA

Previously seen trips

Next departures for Des Moines to Philadelphia on October 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Des Moines (Subway)
Cherry Hill MallNo tags
FlixBus + Greyhound
Des Moines (Subway)
Philadelphia, 199 Spring Garden StNo tags
FlixBus + Greyhound
Des Moines (Subway)
Philadelphia (Logan Square)No tags
FlixBus + Greyhound
Des Moines (Subway)
Frazer - 56-40 Matthews RdNo tags
FlixBus + Greyhound
Des Moines (Subway)
199 Spring Garden St.No tags

Accepted payments

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  • China Union Pay
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  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Des Moines to Philadelphia, PA: Trip Overview

Average Ticket PriceUS$235
Average Bus Trip Duration1d 10h
Number of daily buses5
Earliest bus departure5:30am
Distance1561 km
Latest bus departure9:30am

Des Moines to Philadelphia Bus

With Busbud, comparing and booking tickets for a bus from Des Moines to Philadelphia is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Des Moines to Philadelphia from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Des Moines to Philadelphia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Des Moines - Philadelphia, PA

  1. How far is Des Moines from Philadelphia?

    Des Moines and Philadelphia are 1563 km (969 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Des Moines to Philadelphia?

    Buses departing from Jefferson/Trailways Depot in Des Moines will take you to Philadelphia Airport in Philadelphia.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-07
No data
10-08
US$221
Today
US$255
10-10
No data
10-11
No data
10-12
No data
10-13
No data
10-14
No data
busbud logoThe cheapest trip from Des Moines to Philadelphia, PA was searched and found on Oct 8, 2025 with a price of US$221

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Philadelphia, PA, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Des Moines to Philadelphia.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Philadelphia, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Philadelphia that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Des Moines to Philadelphia while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Des Moines by bus?

Bus from Philadelphia, PA to Des Moines

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