How much is the bus ticket from Des Moines to Philadelphia?

The cheapest bus tickets from Des Moines to Philadelphia start from $128. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Des Moines to Philadelphia?

The average bus trip duration from Des Moines to Philadelphia is 1d 10h, covering a distance of 969 miles (1562 km). The quickest bus can get you there in 1d 2h and is operated by Greyhound .

Which bus companies service the Des Moines to Philadelphia route?

Several major train operators operate on this route with 7 trains available per day.

What is the earliest and latest departure time for the bus from Des Moines to Philadelphia?

The earliest bus departs from Des Moines to Philadelphia at 9:25am. And the latest bus departs at 9:45am.

What are the CO₂ emissions for the bus trip from Des Moines to Philadelphia?

A bus trip from Des Moines to Philadelphia generates an estimated 39 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Des Moines to Philadelphia from $155 | Refundable Tickets

Previously seen trips

Next departures for Des Moines to Philadelphia on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	5:30am	Des Moines (Subway)	2d 2h	8:50am	Philadelphia, 199 Spring Garden St	No tags
FlixBus + Greyhound	Bus	5:30am	Des Moines (Subway)	2d 5h	11:40am	Cherry Hill Mall	No tags
Greyhound + FlixBus	Bus	5:30am	Des Moines (Subway)	2d 2h	8:50am	Philadelphia, 199 Spring Garden St	No tags
FlixBus + Greyhound	Bus	5:30am	Des Moines (Subway)	1d 17h	11:35pm	199 Spring Garden St.	No tags
FlixBus + Greyhound	Bus	5:30am	Des Moines (Subway)	2d 14h	8:35pm	Frazer - 56-40 Matthews Rd	No tags

Get from Des Moines to Philadelphia

This route is served by bus only

The journey takes about 1 day, 10 hours 5 minutes and with fares starting at just $128, it presents an excellent value for a comfortable ride.

7bus per day

1d 10hAverage Duration

969 milesDistance

39kgCO₂ emissions

Where are the popular stops in Des Moines and Philadelphia?

Stops in Des Moines

A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314
Map
B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Map

Stops in Philadelphia

A
Philadelphia Airport
Visit page Map
B
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
Visit page Map
C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA
Map
D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA
Map
E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA
Map
F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Map

Compare bus companies

Greyhound

3.5/587,504 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Des Moines to Philadelphia, PA by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Des Moines to Philadelphia?
The cheapest bus tickets from Des Moines to Philadelphia start from $128. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Philadelphia?
The average bus trip duration from Des Moines to Philadelphia is 1d 10h, covering a distance of 969 miles (1562 km). The quickest bus can get you there in 1d 2h and is operated by Greyhound.
Which bus companies service the Des Moines to Philadelphia route?
Several major train operators operate on this route with 7 trains available per day.
What is the earliest and latest departure time for the bus from Des Moines to Philadelphia?
The earliest bus departs from Des Moines to Philadelphia at 9:25am. And the latest bus departs at 9:45am.
What are the CO₂ emissions for the bus trip from Des Moines to Philadelphia?
A bus trip from Des Moines to Philadelphia generates an estimated 39 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/15

No data

01/16

$184

Today

No data

01/18

No data

01/19

$170

01/20

No data

01/21

No data

01/22

No data

The cheapest trip from Des Moines to Philadelphia, PA was searched and found on Jan 19, 2026 with a price of $170

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Philadelphia, PA, as early as possible.

You can expect to pay from $170 to $185 for a bus ticket from Des Moines to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $170 which is on 2026-01-19.