Bus Tickets from Detroit, MI to Des Moines

Next bus departures

Next departures for Detroit to Des Moines on November 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Detroit Bus Station
Des MoinesCheapestFastest

Last refresh of the prices: Yesterday at 5:18 PM EST.

Get from Detroit to Des Moines

This route is served by bus only

The journey takes about 16 hours 10 minutes, and with fares starting at just $146, it presents an excellent value for a comfortable ride.

1bus per day
16h 10mAverage Duration
874 kmDistance
22kgCO₂ emissions

Frequently asked questions about travelling from Detroit, MI to Des Moines by bus

  1. How far is Detroit from Des Moines?

    The distance between Detroit and Des Moines is around 878 km (545 miles).

  2. What are the departure and arrival locations for buses traveling from Detroit to Des Moines?

    Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Jefferson/Trailways Depot, in Des Moines.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-11
$183
11-12
No data
Today
$216
11-14
No data
11-15
$132
11-16
No data
11-17
No data
11-18
No data
busbud logoThe cheapest trip from Detroit, MI to Des Moines was searched and found on Nov 15, 2025 with a price of $132

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Des Moines, as early as possible.

You can expect to pay from $132 to $216 for a bus ticket from Detroit, MI to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $132 which is on 2025-11-15.

People from around the world trust Busbud

Popular Buses Connecting Detroit

Buses Leaving from Detroit

Buses Going to Detroit

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines