Bus Tickets from Detroit, MI to Des Moines

Next departures

Next departures for Detroit to Des Moines on November 6
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Detroit Bus Station
    		Des MoinesCheapestFastest

    Last refresh of the prices: Yesterday at 8:49 PM EST.

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    Get from Detroit to Des Moines

    This route is served by bus only

    The journey takes about 16 hours 10 minutes and with fares starting at just $102, it presents an excellent value for a comfortable ride.

    1bus per day
    16h 10mAverage Duration
    542 milesDistance
    22kgCO₂ emissions

    Bus Detroit, MI to Des Moines: Trip Overview

    Average ticket price$121
    Average bus trip duration16h 10m
    Number of daily buses1
    Earliest bus departure11:25pm
    Distance542 miles (874 km)

    Detroit to Des Moines Bus

    With Busbud, comparing and booking tickets for a bus from Detroit to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

    We make sure you can find a bus service from Detroit to Des Moines from the most reliable bus companies operating this trip.

    From cheap bus tickets to more luxurious buses traveling from Detroit to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

    Frequently asked questions for your trip Detroit, MI - Des Moines

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    11/02
    $108
    11/03
    No data
    Today
    $111
    11/05
    No data
    11/06
    $97
    11/07
    No data
    11/08
    No data
    11/09
    $99
    busbud logoThe cheapest trip from Detroit, MI to Des Moines was searched and found on Nov 6, 2025 with a price of $97

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Des Moines, as early as possible.

    You can expect to pay from $97 to $111 for a bus ticket from Detroit, MI to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2025-11-06.

    About Bus Travel

    Bus Travel Tips

    Meet and talk to locals at the bus stations while traveling from Detroit to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

    Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Des Moines, get comfy and count the stars.

    Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Des Moines that are otherwise impossible to come by with a plane.

    Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Detroit to Des Moines.

    Did you know?

    The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

    Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

    The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

    Will you be returning to Detroit, MI by bus?

    Bus from Des Moines to Detroit, MI

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