Bus from Detroit, MI to Harrisburg: Tickets & Schedules

Next departures

Next departures for Detroit to Harrisburg on December 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Detroit Bus Station
Harrisburg Bus StationCheapest
Greyhound Lines, Inc.
Detroit Bus Station
Harrisburg Bus StationFastest
Amtrak
Amtrak Station
Harrisburg, PANo tags
Greyhound Lines, Inc.
Detroit Bus Station
Harrisburg Bus StationNo tags
Amtrak
Amtrak Station
Harrisburg, PANo tags

Last refresh of the prices: Last Sunday at 7:51 AM EST.

Get from Detroit to Harrisburg

This route is served by bus only

The journey takes about 12 hours 10 minutes, and with fares starting at just $107, it presents an excellent value for a comfortable ride.

2bus per day
12h 10mAverage Duration
565 kmDistance
14kgCO₂ emissions

Frequently asked questions about travelling from Detroit, MI to Harrisburg by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Detroit to Harrisburg?

    The cheapest bus tickets from Detroit to Harrisburg start from $107. The average price for this route is around $160. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Detroit to Harrisburg?

    The average bus travel time from Detroit to Harrisburg is 12h 10m, covering a distance of 565 km. The quickest bus can get you there in 11h 50m and is operated by Greyhound.

  3. Which bus companies service the Detroit to Harrisburg route?

    Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, Amtrak.

  4. What are the earliest and latest departure times for the bus from Detroit to Harrisburg?

    The earliest bus departs from Detroit to Harrisburg at 6:40am. And the latest bus departs at 10:05pm.

  5. What are the CO₂ emissions for the bus trip from Detroit to Harrisburg?

    A bus trip from Detroit to Harrisburg generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Detroit to Harrisburg?

    According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.

  7. Which bus company has the best Wi-Fi from Detroit to Harrisburg?

    Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.

  8. Which bus company has the best on-time performance from Detroit to Harrisburg?

    According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.

  9. Which bus company has the cleanest buses from Detroit to Harrisburg?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-07
$130
12-08
$101
Today
No data
12-10
$106
12-11
$151
12-12
$175
12-13
$121
12-14
No data
busbud logoThe cheapest trip from Detroit, MI to Harrisburg was searched and found on Dec 8, 2025 with a price of $101

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Harrisburg, as early as possible.

You can expect to pay from $101 to $726 for a bus ticket from Detroit, MI to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $106 which is on 2025-12-10.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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