Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Detroit Bus Station | San Diego (Old Town-FlixBus) | No tags | ||||
Greyhound + FlixBus | Bus | Detroit Bus Station | UCSD Health La Jolla Station | No tags | ||||
FlixBus + Greyhound | Bus | Detroit Bus Station | 5716 Hardy Ave | No tags | ||||
 | Bus | Detroit Bus Station | Greyhound Bus Stop | No tags | ||||
Greyhound + FlixBus | Bus | Detroit Bus Station | Downtown SD (Seaport) | No tags |
Compare 2 ways to go from Detroit to San Diego
Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 2 days, 9 hours 41 minutes, and with fares starting at just $437, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and San Diego?
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Frequently asked questions about travelling from Detroit, MI to San Diego, CA, US by bus
What is the travel distance from Detroit to San Diego?
The distance between Detroit and San Diego is around 3171 km (1967 miles).
What are the departure and arrival locations for buses traveling from Detroit to San Diego?
Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Mission Valley Sheraton, in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to San Diego, CA, US was searched and found on Nov 29, 2025 with a price of $476To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to San Diego, CA, US, as early as possible.
You can expect to pay from $476 to $721 for a bus ticket from Detroit, MI to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $476 which is on 2025-11-29.
What's the cheapest way to go from Detroit, MI to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
