Bus from Detroit, MI to San Diego, CA, US: Tickets & Schedules
Next bus departures
Next departures for Detroit to San Diego on November 25
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Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Detroit Bus Station
San Diego (Old Town-FlixBus)
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Detroit Bus Station
UCSD Health La Jolla Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Detroit Bus Station
UCSD Health La Jolla Station
No tags
Bus
Detroit Bus Station
Greyhound Bus Stop
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Detroit Bus Station
Downtown SD (Seaport)
No tags
Last refresh of the prices: Today at 10:18 AM EST.
Compare 2 ways to go from Detroit to San Diego
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 2 days, 9 hours 41 minutes and with fares starting at just $303, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Detroit, MI to San Diego, CA, US by bus
What is the travel distance from Detroit to San Diego?
The distance separating Detroit and San Diego is 1967 miles (3171 km).
What are the departure and arrival stations when taking the bus from Detroit to San Diego?
The majority of buses traveling from Detroit to San Diego start their journey at Detroit Bus Station and wind up at Mission Valley Sheraton. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in San Diego?
Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are Old Point Loma Lighthouse, San Diego Bay Waterfront, Old Town, USS Midway Museum and Boat Tours in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/23
No data
11/24
No data
Today
$500
11/26
No data
11/27
No data
11/28
No data
11/29
$330
11/30
No data
The cheapest trip from Detroit, MI to San Diego, CA, US was searched and found on Nov 29, 2025 with a price of $330
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to San Diego, CA, US, as early as possible.
You can expect to pay from $330 to $500 for a bus ticket from Detroit, MI to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $330 which is on 2025-11-29.
What's the cheapest way to go from Detroit, MI to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from Detroit, MI to San Diego, CA, US was searched and found on Nov 29, 2025 with a price of $330
The bus is the cheapest travel choice for this destination
