Bus Tickets from Durham (NC), US to Harrisburg

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MonJun 9
from US$81
TueJun 10
from US$74
WedJun 11
from US$79
ThuJun 12
from US$76
FriJun 13
from US$92
SatJun 14
from US$78
SunJun 15
MonJun 16

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 10 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: June 11 at
    Destination city: Harrisburg
    Destination location: Harrisburg Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 10 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: June 10 at
    Destination city: Harrisburg
    Destination location: Harrisburg Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 10 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: June 10 at
    Destination city: Harrisburg
    Destination location: Harrisburg Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 10 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: June 10 at
    Destination city: Harrisburg
    Destination location: Harrisburg Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 10 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: June 11 at
    Destination city: Harrisburg
    Destination location: Harrisburg
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Tuesday at 9:57 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Durham to Harrisburg

Bus
Average PriceUS$68 - US$158Average Duration17h 30m
13kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$133 - US$133Average Duration13h 56m
46kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Durham to Harrisburg

Among the sustainable travel choices, the train stands out as a good way to reach Harrisburg. The journey takes about 13 hours 56 minutes, and with fares starting at just US$133, it presents an excellent value for a comfortable ride.

1train per day
13h 56mAverage Duration
US$133Cheapest ticket
46kgCO₂ emissions

Bus Durham to Harrisburg: Trip Overview

Average Ticket PriceUS$86
Average Bus Trip Duration17h 30m
Number of daily buses5
Earliest bus departure2:45am
Distance506 km
Latest bus departure9:55pm

Durham to Harrisburg Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Durham to Harrisburg.

We make sure you can find a bus service from Durham to Harrisburg from the most reliable bus companies operating this trip.

Discover how much the bus trip from Durham to Harrisburg will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Durham (NC), US - Harrisburg

  1. How long does it take to get to Harrisburg from Durham by bus?

    The trip from Durham to Harrisburg will take on average 17h 30m. The fastest bus on this trip will get to Harrisburg in 11h 10m

  2. What is the distance between Durham and Harrisburg?

    It's about 508 km (315 miles) from Durham to Harrisburg.

  3. What are the departure and arrival locations for buses traveling from Durham to Harrisburg?

    Buses traveling this route start their trip at Durham Greyhound Bus Station, in Durham, and end it at Harrisburg Bieber Greyhound Station, in Harrisburg.

  4. What is the cheapest way to travel from Durham to Harrisburg?

    Taking the bus is the most budget-friendly option to travel from Durham to Harrisburg. The ticket price for this bus starts at US$68, making this your best choice for this trip.

  5. How much is the bus from Durham to Harrisburg?

    Taking the bus from Durham to Harrisburg costs on average US$86.

  6. Is it possible to travel by overnight bus from Durham to Harrisburg?

    Yes! Catch buses leaving from Durham until 9:55pm and reaching Harrisburg on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-05
US$74
06-06
No data
Today
US$81
06-08
US$132
06-09
US$74
06-10
US$67
06-11
US$72
06-12
US$68
busbud logoThe cheapest trip from Durham to Harrisburg was searched and found on Jun 10, 2025 with a price of US$67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham to Harrisburg, as early as possible.

You can expect to pay from US$67 to US$159 for a bus ticket from Durham to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at US$67 which is on 2025-06-10.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Durham to Harrisburg but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Durham to Harrisburg, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Durham to Harrisburg will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Harrisburg.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Durham to Harrisburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham by bus?

Bus from Durham to Harrisburg

You can also go to Harrisburg by train

Train from Durham to Harrisburg

Why choose Busbud?

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