Bus Tickets from Florence, SC, US to Greenville, SC

Next departures

Next departures for Florence to Greenville on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus station
1116 Woodruff RdCheapest
FlixBus + Greyhound Lines, Inc.
Florence, SC
1116 Woodruff RdFastest
FlixBus
Florence, SC
1116 Woodruff RdNo tags

Last refresh of the prices: Last Monday at 1:39 PM EDT.

Accepted payments

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Compare 2 ways to go from Florence to Greenville

Bus
Average PriceUS$69 - US$128Average Duration14h 35m
6kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$130 - US$424Average Duration18h 30m
23kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Florence to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 14 hours 35 minutes, and with fares starting at just US$69, it presents an excellent value for a comfortable ride.

3bus per day
14h 35mAverage Duration
US$69Cheapest ticket
6kgCO₂ emissions

Bus Florence, SC, US to Greenville, SC: Trip Overview

Average Ticket PriceUS$115
Average Bus Trip Duration14h 35m
Number of daily buses3
Earliest bus departure12:05am
Distance243 km
Latest bus departure4:15pm

Florence to Greenville Bus

With Busbud, comparing and booking tickets for a bus from Florence to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Greenville.

Discover how much the bus trip from Florence to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Florence, SC, US - Greenville, SC

  1. What is the distance between Florence and Greenville?

    It's about 263 km (163 miles) from Florence to Greenville.

  2. What are the departure and arrival locations for buses traveling from Florence to Greenville?

    Buses departing from Florence Bus Station in Florence will take you to Guadalajara Supermarket Bus Stop in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-07
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10-08
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Today
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10-10
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10-11
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10-12
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10-13
US$119
10-14
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busbud logoThe cheapest trip from Florence, SC, US to Greenville, SC was searched and found on Oct 13, 2025 with a price of US$119

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Greenville, SC, as early as possible.

You can expect to pay from US$119 to US$119 for a bus ticket from Florence, SC, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$119 which is on 2025-10-13.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Florence to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Greenville.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Florence to Greenville will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Greenville.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Florence, SC, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Greenville, SC to Florence, SC, US

You can also go to Greenville, SC by train

Train from Florence, SC, US to Greenville, SC

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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