What is the distance between Florence and Pittsburgh?

The distance covered from Florence to Pittsburgh is 695 km (431 miles).

What are the departure and arrival locations for buses traveling from Florence to Pittsburgh?

Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Intermodal Station, in Pittsburgh.

Bus Florence to Pittsburgh from $118 | Refundable Tickets

Previously seen trips

Next departures for Florence to Pittsburgh on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:15pm	Bus station	20h 30m	12:45pm	Pittsburgh Intermodal Station	No tags
Greyhound + FlixBus	Bus	11:59pm	Florence, SC	23h 56m	11:55pm	Pittsburgh Intermodal Station	No tags
	Bus	4:15pm	Bus station	20h 30m	12:45pm	Pittsburgh Intermodal Station	No tags
Greyhound + FlixBus	Bus	11:59pm	Florence, SC	23h 56m	11:55pm	Pittsburgh Intermodal Station	No tags
Greyhound + FlixBus	Bus	11:59pm	Florence, SC	23h 56m	11:55pm	Pittsburgh Intermodal Station	No tags

Compare 2 ways to go from Florence to Pittsburgh

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Pittsburgh. The journey takes about 17 hours 45 minutes, and with fares starting at just $124, it presents an excellent value for a comfortable ride.

1bus per day

17h 45mAverage Duration

696 kmDistance

17kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$124 - $547	Average Duration17h 45m	CO₂ emissions 17kg CO₂e
Train	Average Price$288 - $582	Average Duration1d	CO₂ emissions 63kg CO₂e

Where are the popular stops in Florence and Pittsburgh?

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA

Compare bus companies

FlixBus

3.5/511,428 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Florence, SC, US to Pittsburgh by bus

What is the distance between Florence and Pittsburgh?
The distance covered from Florence to Pittsburgh is 695 km (431 miles).
What are the departure and arrival locations for buses traveling from Florence to Pittsburgh?
Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Intermodal Station, in Pittsburgh.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-22

$245

11-23

No data

Today

$217

11-25

$184

11-26

No data

11-27

No data

11-28

No data

11-29

No data

The cheapest trip from Florence, SC, US to Pittsburgh was searched and found on Nov 25, 2025 with a price of $184

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Pittsburgh, as early as possible.

You can expect to pay from $184 to $245 for a bus ticket from Florence, SC, US to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $184 which is on 2025-11-25.