Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Rosa Parks Station | Key Largo | CheapestFastest |
Last refresh of the prices: Yesterday at 11:11 AM EST.
Get from Gainesville to Key Largo
The journey takes about 12 hours 25 minutes, and with fares starting at just $124, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87430 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $145
Frequently asked questions about travelling from Gainesville, FL to Key Largo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Gainesville to Key Largo?
The cheapest bus tickets from Gainesville to Key Largo start from $124. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Gainesville to Key Largo?
The average bus travel time from Gainesville to Key Largo is 12h 25m, covering a distance of 540 km. The quickest bus can get you there in 11h 55m and is operated by Greyhound.
Which bus companies service the Gainesville to Key Largo route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Gainesville to Key Largo?
The earliest bus departs from Gainesville to Key Largo at 12:35am. And the latest bus departs at 10:40pm.
What are the CO₂ emissions for the bus trip from Gainesville to Key Largo?
A bus trip from Gainesville to Key Largo generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville, FL to Key Largo was searched and found on Dec 13, 2025 with a price of $246To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Key Largo, as early as possible.
