- Harrisburg to Knoxville buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Harrisburg Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Harrisburg Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Harrisburg Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Harrisburg Bus Station | Knoxville Bus Station | No tags | ||||
![]() | Bus | Harrisburg Bus Station | Knoxville Bus Station | No tags |
Get from Harrisburg to Knoxville
The journey takes about 23 hours 15 minutes, and with fares starting at just $252, it presents an excellent value for a comfortable ride.
Where are the popular stops in Harrisburg and Knoxville?
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87518 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $252
Frequently asked questions about travelling from Harrisburg to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Harrisburg to Knoxville?
The cheapest bus tickets from Harrisburg to Knoxville start from $252. The average price for this route is around $295. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Harrisburg to Knoxville?
The average bus travel time from Harrisburg to Knoxville is 23h 15m, covering a distance of 774 km. The quickest bus can get you there in 22h 40m and is operated by Greyhound.
Which bus companies service the Harrisburg to Knoxville route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Harrisburg to Knoxville?
The earliest bus departs from Harrisburg to Knoxville at 2:50pm. And the latest bus departs at 8:15pm.
What are the CO₂ emissions for the bus trip from Harrisburg to Knoxville?
A bus trip from Harrisburg to Knoxville generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.






