Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Houston Bus Station | Greyhound Bus Stop | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | UCSD Health La Jolla Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | San Diego (Old Town-FlixBus) | No tags | ||||
| Bus | Houston Bus Station | Greyhound Bus Stop | No tags | ||||
Valley Transit + Greyhound Lines, Inc. + FlixBus | Bus | Hillcroft Ave & Southwest Freeway | San Diego (Old Town-FlixBus) | No tags |
Last refresh of the prices: Yesterday at 4:03 PM CST.
Compare 2 ways to go from Houston to San Diego
Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 1 day, 16 hours 55 minutes, and with fares starting at just $293, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and San Diego?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B2121 Main St, Houston, TX 77002
- C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
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Frequently asked questions about travelling from Houston, US to San Diego, CA, US by bus
What is the travel distance from Houston to San Diego?
The distance between Houston and San Diego is around 2097 km (1300 miles).
What are the departure and arrival locations for buses traveling from Houston to San Diego?
Buses traveling this route start their trip at Hillcroft Ave & Southwest Freeway, in Houston, and end it at Mission Valley Sheraton, in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to San Diego, CA, US was searched and found on Nov 26, 2025 with a price of $246To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to San Diego, CA, US, as early as possible.
You can expect to pay from $246 to $624 for a bus ticket from Houston, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $246 which is on 2025-11-26.
What's the cheapest way to go from Houston, US to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
