Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | Downtown Gray & Smith | Cheapest | ||||
 | Bus | Knoxville Bus Station | Houston Bus Station | Fastest | ||||
| Bus | Knoxville Bus Station | Houston Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | Houston Uptown/Upper Kirby | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | Baytown, 6800 Thompson Rd | No tags |
Last refresh of the prices: Last Monday at 11:26 PM EST.
Get from Knoxville to Houston
The journey takes about 23 hours 55 minutes, and with fares starting at just $202, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Houston?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Compare bus companies
Based on 87422 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $202
Greyhound Knoxville Houston recent customer reviews
Got into Atlanta and bus was cancelled set there 22hrs before rerouted on another trip. First time using a bus for travel and will be the last time
Rachelle N.
Facilities were very dirty and passengers were not respectful to the rules. I feel as if the bus should be monitored by one of the greyhound employees while the other is driving. Staff was not very friendly but instead always in a rush.
Louana W.
Was ok but not the best
Anthony F.
Frequently asked questions about travelling from Knoxville, TN to Houston, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Houston?
The cheapest bus tickets from Knoxville to Houston start from $202. The average price for this route is around $309. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Houston?
The average bus travel time from Knoxville to Houston is 23h 55m, covering a distance of 1278 km. The quickest bus can get you there in 23h 50m and is operated by Greyhound.
Which bus companies service the Knoxville to Houston route?
Several major bus companies operate on this route with 8 buses available per day.
What are the earliest and latest departure times for the bus from Knoxville to Houston?
The earliest bus departs from Knoxville to Houston at 6:10pm. And the latest bus departs at 10:50pm.
What are the CO₂ emissions for the bus trip from Knoxville to Houston?
A bus trip from Knoxville to Houston generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Houston, US was searched and found on Dec 10, 2025 with a price of $203To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Houston, US, as early as possible.
You can expect to pay from $203 to $252 for a bus ticket from Knoxville, TN to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at $213 which is on 2025-12-11.
