Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | The Florida Mall | Cheapest | ||||
 | Bus | Knoxville Bus Station | Orlando Bus Station | Fastest |
Last refresh of the prices: Last Sunday at 10:51 PM EST.
Get from Knoxville to Orlando
The journey takes about 19 hours 50 minutes, and with fares starting at just $92, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Orlando?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Compare bus companies
Based on 87403 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $92
Frequently asked questions about travelling from Knoxville, TN to Orlando by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Orlando?
The cheapest bus tickets from Knoxville to Orlando start from $92. The average price for this route is around $175. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Orlando?
The average bus travel time from Knoxville to Orlando is 19h 50m, covering a distance of 872 km. The quickest bus can get you there in 13h 40m and is operated by Greyhound.
Which bus companies service the Knoxville to Orlando route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Knoxville to Orlando?
The earliest bus departs from Knoxville to Orlando at 6:10pm. And the latest bus departs at 7:05pm.
What are the CO₂ emissions for the bus trip from Knoxville to Orlando?
A bus trip from Knoxville to Orlando generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Orlando was searched and found on Dec 3, 2025 with a price of $192To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Orlando, as early as possible.
You can expect to pay from $192 to $372 for a bus ticket from Knoxville, TN to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $192 which is on 2025-12-03.
