Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | The Florida Mall | Cheapest | ||||
 | Bus | Knoxville Bus Station | Orlando Bus Station | Fastest |
Last refresh of the prices: Today at 1:49 PM EST.
Get from Knoxville to Orlando
The journey takes about 19 hours 50 minutes, and with fares starting at just $92, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Orlando?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Compare bus companies
Based on 87397 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $92
Frequently asked questions about travelling from Knoxville, TN to Orlando by bus
How far is Knoxville from Orlando?
The distance between Knoxville and Orlando is around 861 km (534 miles).
What are the departure and arrival locations for buses traveling from Knoxville to Orlando?
Buses traveling this route start their trip at 100 Kirkwood St, in Knoxville, and end it at Orlando Bus Station, in Orlando.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Orlando was searched and found on Nov 27, 2025 with a price of $234To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Orlando, as early as possible.
You can expect to pay from $234 to $398 for a bus ticket from Knoxville, TN to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $234 which is on 2025-11-27.
