Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Knoxville Bus Station | The Florida Mall | Cheapest | |||||
 | Knoxville Bus Station | Orlando Bus Station | Fastest | |||||
| Knoxville Bus Station | Orlando Bus Station | No tags |
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Bus Knoxville, TN to Orlando: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Knoxville to Orlando Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Orlando.
We make sure you can find a bus service from Knoxville to Orlando from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Orlando from Knoxville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Knoxville and Orlando?
Frequently asked questions for your trip Knoxville, TN - Orlando
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Orlando was searched and found on Aug 27, 2025 with a price of $86To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Orlando, as early as possible.
You can expect to pay from $86 to $156 for a bus ticket from Knoxville, TN to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $86 which is on 2025-08-27.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Orlando but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Knoxville to Orlando, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Orlando.
Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Orlando while indulging in miles on end of beautiful scenic views.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top traveled bus routes
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Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Orlando
- Bus from Knoxville to Lexington
- Bus Knoxville - Chicago
- Knoxville - Greenville
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - New York City
- Bus from Knoxville to Memphis
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Miami
- Bus Knoxville - Jackson
- Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Asheville - Knoxville
- New York City - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Cookeville - Knoxville
- Bus from Lexington to Knoxville
- Bus Dallas - Knoxville
- Dayton - Knoxville
Popular Buses Connecting Orlando
Buses Leaving from Orlando
- Bus from Orlando to Melbourne
- Bus Orlando - Tampa
- Orlando - Jacksonville
- Bus from Orlando to Jacksonville
- Bus Orlando - Daytona Beach
- Orlando - Gainesville
- Bus from Orlando to Ocala
- Bus Orlando - Bradenton
- Orlando - Tallahassee
- Bus from Orlando to New York City
- Bus Orlando - West Palm Beach
- Orlando - Port Saint Lucie
- Bus from Orlando to Fort Myers
Buses Going to Orlando
- Bus from Tampa to Orlando
- Bus Atlanta - Orlando
- Chicago - Orlando
- Bus from Norman to Orlando
- Bus Houston - Orlando
- Ocala - Orlando
- Bus from Hollywood to Orlando
- Bus Gainesville - Orlando
- Bradenton - Orlando
- Bus from Jacksonville to Orlando
- Bus New York City - Orlando
- Pompano Beach - Orlando
- Bus from Naples to Orlando
- Bus Port Saint Lucie - Orlando