Bus from Lafayette, IN to St. Louis: Tickets & Schedules

Next bus departures

Next departures for Lafayette to St. Louis on November 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Lafayette Bus Stop
Gateway StationCheapest
Greyhound Lines, Inc.Bus
Lafayette Bus Stop
Gateway StationFastest
Greyhound Lines, Inc. + FlixBus
Bus
Lafayette Bus Stop
Gateway StationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Lafayette Bus Stop
Gateway StationNo tags

Last refresh of the prices: Yesterday at 4:13 AM EST.

Get from Lafayette to St. Louis

This route is served by bus only

The journey takes about 9 hours 55 minutes, and with fares starting at just $62, it presents an excellent value for a comfortable ride.

4bus per day
9h 55mAverage Duration
348 kmDistance
9kgCO₂ emissions

Frequently asked questions about travelling from Lafayette, IN to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Lafayette to St. Louis?

    The cheapest bus tickets from Lafayette to St. Louis start from $62. The average price for this route is around $91. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Lafayette to St. Louis?

    The average bus travel time from Lafayette to St. Louis is 9h 55m, covering a distance of 348 km. The quickest bus can get you there in 6h 35m and is operated by Greyhound.

  3. Which bus companies service the Lafayette to St. Louis route?

    Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.

  4. What are the earliest and latest departure times for the bus from Lafayette to St. Louis?

    The earliest bus departs from Lafayette to St. Louis at 9:35am. And the latest bus departs at 9:25pm.

  5. What are the CO₂ emissions for the bus trip from Lafayette to St. Louis?

    A bus trip from Lafayette to St. Louis generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Lafayette to St. Louis?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.

  7. Which bus company has the best Wi-Fi from Lafayette to St. Louis?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Lafayette to St. Louis?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Lafayette to St. Louis?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-26
$81
11-27
$67
Today
$103
11-29
$100
11-30
$110
12-01
No data
12-02
No data
12-03
$52
busbud logoThe cheapest trip from Lafayette, IN to St. Louis was searched and found on Dec 3, 2025 with a price of $52

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, IN to St. Louis, as early as possible.

You can expect to pay from $52 to $121 for a bus ticket from Lafayette, IN to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-12-03.

People from around the world trust Busbud

‌