Bus Tickets from Louisville to Chicago

Next departures

Next departures for Louisville to Chicago on November 11
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    Louisville, KY
    Downtown Greyhound StationCheapest
    FlixBus
      Louisville, KY
      Chicago 95Th & Dan RyanFastest
      Amtrak
        Louisville, KY
        Chicago (Union Station), ILNo tags
        Greyhound Lines, Inc.
          Louisville, KY
          Downtown Greyhound StationNo tags
          FlixBus
            Louisville, KY
            Downtown Greyhound StationNo tags

            Last refresh of the prices: Today at 10:29 PM EST.

            Get from Louisville to Chicago

            This route is served by bus only

            The journey takes about 6 hours 40 minutes, and with fares starting at just $55, it presents an excellent value for a comfortable ride.

            18bus per day
            6h 40mAverage Duration
            418 kmDistance
            10kgCO₂ emissions

            Frequently asked questions about travelling from Louisville to Chicago by bus

            1. What is the travel distance from Louisville to Chicago?

              The distance covered from Louisville to Chicago is 432 km (268 miles).

            2. What are the departure and arrival locations for buses traveling from Louisville to Chicago?

              Buses traveling this route start their trip at Louisville Greyhound Bus Station, in Louisville, and end it at Downtown Greyhound Station, in Chicago.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11-06
            $80
            11-07
            $87
            Today
            $80
            11-09
            $96
            11-10
            $65
            11-11
            $61
            11-12
            $58
            11-13
            $61
            busbud logoThe cheapest trip from Louisville to Chicago was searched and found on Nov 12, 2025 with a price of $58

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago, as early as possible.

            You can expect to pay from $58 to $205 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $58 which is on 2025-11-12.

            Usually Greyhound, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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