What is the travel distance from Louisville to Chicago?

The distance covered from Louisville to Chicago is 432 km (268 miles).

What are the departure and arrival locations for buses traveling from Louisville to Chicago?

Buses traveling this route start their trip at Louisville Greyhound Bus Station, in Louisville, and end it at Downtown Greyhound Station, in Chicago.

Bus Louisville to Chicago from $52 | Refundable Tickets

Next departures

Next departures for Louisville to Chicago on November 10
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	7:30pm	Louisville, KY	5h 20m	11:50pm	Chicago 95Th & Dan Ryan	CheapestFastest
	2:55am	Louisville, KY	6h	7:55am	Chicago (Union Station), IL	No tags
	2:50am	Louisville, KY	6h 25m	8:15am	Downtown Greyhound Station	No tags
	4:50am	Louisville, KY	7h 40m	11:30am	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	2:50am	Louisville, KY	8h	9:50am	Chicago 95Th & Dan Ryan	No tags

Next departures for Louisville to Chicago on November 11
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
2:35pm	Louisville, KY	6h 35m	8:10pm	Downtown Greyhound Station	Cheapest
7:30pm	Louisville, KY	5h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
2:55am	Louisville, KY	6h	7:55am	Chicago (Union Station), IL	No tags
2:50am	Louisville, KY	6h 25m	8:15am	Downtown Greyhound Station	No tags
4:50am	Louisville, KY	7h 40m	11:30am	Downtown Greyhound Station	No tags

Next departures for Louisville to Chicago on November 12
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
2:35pm	Louisville, KY	6h 35m	8:10pm	Downtown Greyhound Station	Cheapest
7:30pm	Louisville, KY	5h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
2:55am	Louisville, KY	6h	7:55am	Chicago (Union Station), IL	No tags
2:50am	Louisville, KY	6h 25m	8:15am	Downtown Greyhound Station	No tags
4:50am	Louisville, KY	7h 40m	11:30am	Downtown Greyhound Station	No tags

Next departures for Louisville to Chicago on November 13
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
8:00am	Louisville, KY	6h 40m	1:40pm	Chicago 95Th & Dan Ryan	Cheapest
7:30pm	Louisville, KY	5h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
2:55am	Louisville, KY	6h	7:55am	Chicago (Union Station), IL	No tags
2:50am	Louisville, KY	6h 25m	8:15am	Downtown Greyhound Station	No tags
4:50am	Louisville, KY	7h 40m	11:30am	Downtown Greyhound Station	No tags

Next departures for Louisville to Chicago on November 14
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
10:10am	Louisville, KY	6h 5m	3:15pm	Downtown Greyhound Station	Cheapest
7:30pm	Louisville, KY	5h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
2:55am	Louisville, KY	6h	7:55am	Chicago (Union Station), IL	No tags
2:50am	Louisville, KY	6h 25m	8:15am	Downtown Greyhound Station	No tags
4:50am	Louisville, KY	7h 40m	11:30am	Downtown Greyhound Station	No tags

Next departures for Louisville to Chicago on November 15
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
8:00am	Louisville, KY	6h 40m	1:40pm	Chicago 95Th & Dan Ryan	Cheapest
7:30pm	Louisville, KY	5h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
2:55am	Louisville, KY	6h	7:55am	Chicago (Union Station), IL	No tags
2:50am	Louisville, KY	6h 25m	8:15am	Downtown Greyhound Station	No tags
4:50am	Louisville, KY	7h 40m	11:30am	Downtown Greyhound Station	No tags

Next departures for Louisville to Chicago on November 16
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	2:50am	Louisville, KY	8h	9:50am	Chicago 95Th & Dan Ryan	Cheapest
	7:30pm	Louisville, KY	5h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
	2:55am	Louisville, KY	6h	7:55am	Chicago (Union Station), IL	No tags
	2:50am	Louisville, KY	6h 25m	8:15am	Downtown Greyhound Station	No tags
	4:50am	Louisville, KY	7h 40m	11:30am	Downtown Greyhound Station	No tags

Last refresh of the prices: Today at 10:29 PM EST.

Get from Louisville to Chicago

This route is served by bus only

The journey takes about 6 hours 40 minutes, and with fares starting at just $55, it presents an excellent value for a comfortable ride.

18bus per day

6h 40mAverage Duration

418 kmDistance

10kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,359 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

According to 23 reviews, Greyhound received a 3.3-star rating for this journey. Travellers were especially satisfied with the staff and the departure location, but some complained about the seats. Greyhound ticket prices on this trip start at $55

Greyhound Louisville Chicago recent customer reviews

The bus was 30 minutes late, there were too many people on board, leaving a couple to stand. Then the driver had to slam on his brakes and I don’t know how the standing people didn’t get thrown up front. At one point the driver was getting on the interstate going the wrong way, until people started yelling at him. Absolutely not the best ride.

Reese W.

October 25, 2023

Mobile chargers and WiFi was not working at all despite the fact that same were informed to be working conditions

Muhammad Amir B.

February 6, 2020

This was the worst ride I have ever had. Negligence and just overall lateness. The trip should have taken 7 hours. It took over 11! Not acceptable

Cydney B.

May 23, 2019

FlixBus

3.5/511,240 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Amtrak

4/55,572 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Louisville and Chicago?

Stops in Louisville

A - Louisville Greyhound Bus Station

Stops in Chicago

A - Downtown Greyhound Station

B - Chicago O'Hare International Airport

C - Polk St & Canal St

D - Tornado Bus S Kedzie Ave

E - Cumberland CTA

F - Turimex California Ave

Frequently asked questions about travelling from Louisville to Chicago by bus

What is the travel distance from Louisville to Chicago?
The distance covered from Louisville to Chicago is 432 km (268 miles).
What are the departure and arrival locations for buses traveling from Louisville to Chicago?
Buses traveling this route start their trip at Louisville Greyhound Bus Station, in Louisville, and end it at Downtown Greyhound Station, in Chicago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-06

$80

11-07

$87

Today

$80

11-09

$96

11-10

$65

11-11

$61

11-12

$58

11-13

$61

The cheapest trip from Louisville to Chicago was searched and found on Nov 12, 2025 with a price of $58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Chicago, as early as possible.

You can expect to pay from $58 to $205 for a bus ticket from Louisville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $58 which is on 2025-11-12.

Usually Greyhound, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

Top travelled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.