Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Lowell, MA | Florence, SC | ||||
 | Bus | Lowell, MA | Bus station |
Get from Lowell to Florence
The journey takes about 23 hours 58 minutes, and with fares starting at just $395, it presents an excellent value for a comfortable ride.
Bus stations and stops in Lowell and Florence
Stops in Lowell
- A
Regional Transit Center Bus Stop
101 Thorndike St, Lowell, MA 01852
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Based on 88050 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $395
Frequently asked questions about travelling from Lowell to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lowell to Florence?
The cheapest bus tickets from Lowell to Florence start from $395. The average price for this route is around $395. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lowell to Florence?
The average bus travel time from Lowell to Florence is 23h 58m, covering a distance of 1192 km. The quickest bus can get you there in 23h 58m and is operated by Greyhound.
Which bus companies service the Lowell to Florence route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Lowell to Florence?
The earliest bus departs from Lowell to Florence at 12:01pm. And the latest bus departs at 12:01pm.
What are the CO₂ emissions for the bus trip from Lowell to Florence?
A bus trip from Lowell to Florence generates an estimated 29.797375 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lowell to Florence, SC, US was searched and found on Aug 9, 2026 with a price of $385To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lowell to Florence, SC, US, as early as possible.
