Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Perrache | Calle Navas de Tolosa, 2 | Cheapest | ||||
 | Bus | Lyon | Santander (Estacion de Autobuses) | Fastest | ||||
| Bus | Perrache | Calle Navas de Tolosa, 2 | No tags | ||||
| Bus | Lyon (Gerland) | Santander (Estacion de Autobuses) | No tags | ||||
| Bus | Aéroport LYS | Santander (Estacion de Autobuses) | No tags |
Last refresh of the prices: Last Saturday at 8:40 PM CET.
Compare 2 ways to go from Lyon to Santander
Among the sustainable travel choices, the Bus stands out as a good way to reach Santander. The journey takes about 19 hours 35 minutes, and with fares starting at just $124, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$124 - $258 | Average Duration19h 35m | 18kg CO₂e | ||
Carpool | Average Price$102 - $102 | Average Duration11h | 31kg CO₂e |
Where are the popular stops in Lyon and Santander?
Stops in Lyon
- ARue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Compare bus companies
Frequently asked questions about travelling from Lyon to Santander by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lyon to Santander?
The cheapest bus tickets from Lyon to Santander start from $124. The average price for this route is around $203. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lyon to Santander?
The average bus travel time from Lyon to Santander is 19h 35m, covering a distance of 730 km. The quickest bus can get you there in 17h 45m and is operated by FlixBus.
Which bus companies service the Lyon to Santander route?
What are the earliest and latest departure times for the bus from Lyon to Santander?
The earliest bus departs from Lyon to Santander at 5:10am. And the latest bus departs at 5:30pm.
What are the CO₂ emissions for the bus trip from Lyon to Santander?
A bus trip from Lyon to Santander generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Lyon to Santander?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61372 reviews.
Which bus company has the best Wi-Fi from Lyon to Santander?
Based on Busbud reviews, the bus company ALSA has the highest Wi-Fi rating with a score of 3.5.
Which bus company has the best on-time performance from Lyon to Santander?
According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Lyon to Santander?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lyon to Santander was searched and found on Mar 10, 2026 with a price of $65To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Santander, as early as possible.
You can expect to pay from $65 to $194 for a bus ticket from Lyon to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at $65 which is on 2026-03-10.
