Is there a way to reach Santander from Lyon without flying?

The bus is the best choice to get to Santander without flying. The bus trip is an affordable, safe and convenient way to travel between the two cities. You also have the choice of using carpooling services.

How long is the bus trip from Lyon to Santander?

The average travel time from Lyon to Santander is about 20h 5m, but the fastest bus can get you there in about 17h 50m. This is the time it takes to travel the 454 miles (732 km) that separate the two cities.

What is the distance between Lyon and Santander?

About 454 miles (732 km) separate Lyon and Santander.

What are the departure and arrival stations when taking the bus from Lyon to Santander?

If you're headed to Santander from Lyon, chances are that your bus will leave from Perrache and arrive at Calle Navas de Tolosa, 2. These are the primary departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What is the cheapest way to go from Lyon to Santander?

The cheapest way to travel this route is by bus. $111 is the starting point for the cost-effective bus ride to Santander from Lyon.

What is the ticket price for the bus trip from Lyon to Santander?

The average price of a one-way ticket from Lyon to Santander is $140. In the last 30 days, the prices ranged from $111 to $208, so it's good to do your research before booking.

Lyon to Santander Bus Tickets

TodayMay 13

TomorrowMay 14

ThuMay 15

FriMay 16

SatMay 17

from $52

SunMay 18

MonMay 19

TueMay 20

Cheap buses leaving Saturday

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: May 17 at 5:10am
Departure city: Lyon
Departure location: Perrache
Arrival time: May 18 at 1:15am
Destination city: Santander
Destination location: Calle Navas de Tolosa, 2
Operated by: ALSA INTERNACIONAL
Vehicle: BusDuration: 20h 5m
This trip is recommended because it is: Fastest
Departure time: May 17 at 5:10am
Departure city: Lyon
Departure location: Perrache
Arrival time: May 18 at 1:15am
Destination city: Santander
Destination location: Calle Navas de Tolosa, 2
Operated by: ALSA INTERNACIONAL
Vehicle: BusDuration: 20h 5m
Departure time: May 17 at 5:10am
Departure city: Lyon
Departure location: Perrache
Arrival time: May 18 at 1:15am
Destination city: Santander
Destination location: Calle Navas de Tolosa, 2
Operated by: ALSA INTERNACIONAL
Vehicle: BusDuration: 20h 5m

Accepted payments

Compare 2 ways to go from Lyon to Santander.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$111 - $208	Average Duration20h 5m	CO₂ emissions 18kg CO₂e5 out of 5 stars	Most eco-friendly
Carpool	Average Price$74 - $74	Average Duration11h	CO₂ emissions 31kg CO₂e4 out of 5 stars	CheapestFastest

Busbud recommends carpooling from Lyon to Santander

Among the sustainable travel choices, the carpool stands out as the good way to reach Santander. The journey takes about 11 hours and with fares starting at just $74, it presents an excellent value for a comfortable ride.

1carpool per day

11hAverage Duration

$74Cheapest ticket

31kgCO₂ emissions

Bus Lyon to Santander: Trip Overview

Average ticket price$140

Average bus trip duration20h 5m

Number of daily buses1

Earliest bus departure5:10am

Distance452 miles (729 km)

Latest bus departure5:55pm

Compare bus companies

FlixBus

3.5/58,607 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.6

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

ALSA

4.5/559,205 reviews

Staff4.7

Timeliness4.4

Cleanliness4.7

Wifi3.5

BlaBlaCar Bus

3.5/510,208 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

Wifi2.5

ES bus companies: FlixBus, BlaBlaCar Bus, ALSA, Rede Expressos, Trenitalia, Sindbad, MarinoBus

Lyon to Santander Bus

Busbud helps you find a bus from Lyon to Santander. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Lyon to Santander from the most reliable bus companies operating this trip.

Discover how much the bus trip from Lyon to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Lyon and Santander?

Stops in Lyon

A - Perrache

B - Lyon Airport

C - Les Charrières

D - Gare Routière - Lyon Part-Dieu

E - Lyon

F - Quai de Saoune

Stops in Santander

A - Calle Navas de Tolosa, 2

B - Santander Airport

C - Av. de los Castros 43A

D - Calle Camarreal-Ojaiz

E - Av. de Pontejos

F - Estación Marítima

Frequently asked questions for your trip Lyon - Santander

Is there a way to reach Santander from Lyon without flying?
How long is the bus trip from Lyon to Santander?
What is the distance between Lyon and Santander?
What are the departure and arrival stations when taking the bus from Lyon to Santander?
What is the cheapest way to go from Lyon to Santander?
What is the ticket price for the bus trip from Lyon to Santander?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/11

$76

05/12

$81

Today

$53

05/14

$41

05/15

$44

05/16

$52

05/17

$52

05/18

$58

The cheapest trip from Lyon to Santander was searched and found on May 14, 2025 with a price of $41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Santander, as early as possible.

You can expect to pay from $41 to $145 for a bus ticket from Lyon to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at $41 which is on 2025-05-14.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Lyon and Santander!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Santander, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lyon to Santander will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Lyon to Santander.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Lyon by bus?

Bus from Lyon to Santander

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Lyon to Santander